EPHA5

EPH receptor A5, also known as EPHA5, is a human gene.cite web | title = Entrez Gene: EPHA5 EPH receptor A5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2044| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.cite web | title = Entrez Gene: EPHA5 EPH receptor A5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2044| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Zhou R |title=Regulation of topographic projection by the Eph family receptor Bsk (EphA5) and its ligands. |journal=Cell Tissue Res. |volume=290 |issue= 2 |pages= 251–9 |year= 1997 |pmid= 9321686 |doi=
*cite journal | author=Caras IW |title=A link between axon guidance and axon fasciculation suggested by studies of the tyrosine kinase receptor EphA5/REK7 and its ligand ephrin-A5/AL-1. |journal=Cell Tissue Res. |volume=290 |issue= 2 |pages= 261–4 |year= 1997 |pmid= 9321687 |doi=
*cite journal | author=Flanagan JG, Vanderhaeghen P |title=The ephrins and Eph receptors in neural development. |journal=Annu. Rev. Neurosci. |volume=21 |issue= |pages= 309–45 |year= 1998 |pmid= 9530499 |doi= 10.1146/annurev.neuro.21.1.309
*cite journal | author=Zhou R |title=The Eph family receptors and ligands. |journal=Pharmacol. Ther. |volume=77 |issue= 3 |pages= 151–81 |year= 1998 |pmid= 9576626 |doi=
*cite journal | author=Holder N, Klein R |title=Eph receptors and ephrins: effectors of morphogenesis. |journal=Development |volume=126 |issue= 10 |pages= 2033–44 |year= 1999 |pmid= 10207129 |doi=
*cite journal | author=Wilkinson DG |title=Eph receptors and ephrins: regulators of guidance and assembly. |journal=Int. Rev. Cytol. |volume=196 |issue= |pages= 177–244 |year= 2000 |pmid= 10730216 |doi=
*cite journal | author=Xu Q, Mellitzer G, Wilkinson DG |title=Roles of Eph receptors and ephrins in segmental patterning. |journal=Philos. Trans. R. Soc. Lond., B, Biol. Sci. |volume=355 |issue= 1399 |pages= 993–1002 |year= 2001 |pmid= 11128993 |doi= 10.1098/rstb.2000.0635
*cite journal | author=Wilkinson DG |title=Multiple roles of EPH receptors and ephrins in neural development. |journal=Nat. Rev. Neurosci. |volume=2 |issue= 3 |pages= 155–64 |year= 2001 |pmid= 11256076 |doi=
*cite journal | author=Spritz RA, Strunk KM, Lee ST, "et al." |title=A YAC contig spanning a cluster of human type III receptor protein tyrosine kinase genes (PDGFRA-KIT-KDR) in chromosome segment 4q12. |journal=Genomics |volume=22 |issue= 2 |pages= 431–6 |year= 1995 |pmid= 7528718 |doi= 10.1006/geno.1994.1405
*cite journal | author=Fox GM, Holst PL, Chute HT, "et al." |title=cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases. |journal=Oncogene |volume=10 |issue= 5 |pages= 897–905 |year= 1995 |pmid= 7898931 |doi=
*cite journal | author=Davis S, Gale NW, Aldrich TH, "et al." |title=Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. |journal=Science |volume=266 |issue= 5186 |pages= 816–9 |year= 1994 |pmid= 7973638 |doi=
*cite journal | author=Gale NW, Holland SJ, Valenzuela DM, "et al." |title=Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. |journal=Neuron |volume=17 |issue= 1 |pages= 9–19 |year= 1996 |pmid= 8755474 |doi=
*cite journal | author=Miescher GC, Taylor V, Olivieri G, "et al." |title=Extensive splice variation and localization of the EHK-1 receptor tyrosine kinase in adult human brain and glial tumors. |journal=Brain Res. Mol. Brain Res. |volume=46 |issue= 1-2 |pages= 17–24 |year= 1997 |pmid= 9191074 |doi=
*cite journal | author= |title=Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee. |journal=Cell |volume=90 |issue= 3 |pages= 403–4 |year= 1997 |pmid= 9267020 |doi=
*cite journal | author=Stein E, Savaskan NE, Ninnemann O, "et al." |title=A role for the Eph ligand ephrin-A3 in entorhino-hippocampal axon targeting. |journal=J. Neurosci. |volume=19 |issue= 20 |pages= 8885–93 |year= 1999 |pmid= 10516308 |doi=

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