CUL2

CUL2

Cullin 2, also known as CUL2, is a human gene.cite web | title = Entrez Gene: CUL2 cullin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8453| accessdate = ]

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References

Further reading

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*cite journal | author=Kibel A, Iliopoulos O, DeCaprio JA, Kaelin WG |title=Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C. |journal=Science |volume=269 |issue= 5229 |pages= 1444–6 |year= 1995 |pmid= 7660130 |doi=
*cite journal | author=Kipreos ET, Lander LE, Wing JP, "et al." |title=cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. |journal=Cell |volume=85 |issue= 6 |pages= 829–39 |year= 1996 |pmid= 8681378 |doi=
*cite journal | author=Pause A, Lee S, Worrell RA, "et al." |title=The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 6 |pages= 2156–61 |year= 1997 |pmid= 9122164 |doi=
*cite journal | author=Lonergan KM, Iliopoulos O, Ohh M, "et al." |title=Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2. |journal=Mol. Cell. Biol. |volume=18 |issue= 2 |pages= 732–41 |year= 1998 |pmid= 9447969 |doi=
*cite journal | author=Wada H, Yeh ET, Kamitani T |title=Identification of NEDD8-conjugation site in human cullin-2. |journal=Biochem. Biophys. Res. Commun. |volume=257 |issue= 1 |pages= 100–5 |year= 1999 |pmid= 10092517 |doi= 10.1006/bbrc.1999.0339
*cite journal | author=Ohta T, Michel JJ, Schottelius AJ, Xiong Y |title=ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. |journal=Mol. Cell |volume=3 |issue= 4 |pages= 535–41 |year= 1999 |pmid= 10230407 |doi=
*cite journal | author=Pause A, Peterson B, Schaffar G, "et al." |title=Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 17 |pages= 9533–8 |year= 1999 |pmid= 10449727 |doi=
*cite journal | author=Iwai K, Yamanaka K, Kamura T, "et al." |title=Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 22 |pages= 12436–41 |year= 1999 |pmid= 10535940 |doi=
*cite journal | author=Hori T, Osaka F, Chiba T, "et al." |title=Covalent modification of all members of human cullin family proteins by NEDD8. |journal=Oncogene |volume=18 |issue= 48 |pages= 6829–34 |year= 2000 |pmid= 10597293 |doi= 10.1038/sj.onc.1203093
*cite journal | author=Kamura T, Sato S, Iwai K, "et al." |title=Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 19 |pages= 10430–5 |year= 2000 |pmid= 10973499 |doi= 10.1073/pnas.190332597
*cite journal | author=Lyapina S, Cope G, Shevchenko A, "et al." |title=Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. |journal=Science |volume=292 |issue= 5520 |pages= 1382–5 |year= 2001 |pmid= 11337588 |doi= 10.1126/science.1059780
*cite journal | author=Kamura T, Burian D, Yan Q, "et al." |title=Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. |journal=J. Biol. Chem. |volume=276 |issue= 32 |pages= 29748–53 |year= 2001 |pmid= 11384984 |doi= 10.1074/jbc.M103093200
*cite journal | author=Ohh M, Kim WY, Moslehi JJ, "et al." |title=An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells. |journal=EMBO Rep. |volume=3 |issue= 2 |pages= 177–82 |year= 2002 |pmid= 11818338 |doi= 10.1093/embo-reports/kvf028
*cite journal | author=Min JH, Yang H, Ivan M, "et al." |title=Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling. |journal=Science |volume=296 |issue= 5574 |pages= 1886–9 |year= 2002 |pmid= 12004076 |doi= 10.1126/science.1073440
*cite journal | author=Brower CS, Sato S, Tomomori-Sato C, "et al." |title=Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 16 |pages= 10353–8 |year= 2002 |pmid= 12149480 |doi= 10.1073/pnas.162424199
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Min KW, Hwang JW, Lee JS, "et al." |title=TIP120A associates with cullins and modulates ubiquitin ligase activity. |journal=J. Biol. Chem. |volume=278 |issue= 18 |pages= 15905–10 |year= 2003 |pmid= 12609982 |doi= 10.1074/jbc.M213070200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, "et al." |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462
*cite journal | author=Yan Q, Kamura T, Cai Y, "et al." |title=Identification of Elongin C and Skp1 sequences that determine Cullin selection. |journal=J. Biol. Chem. |volume=279 |issue= 41 |pages= 43019–26 |year= 2004 |pmid= 15280393 |doi= 10.1074/jbc.M408018200

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