- ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide, also known as ATP5B, is a human
gene .cite web | title = Entrez Gene: ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=506| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.cite web | title = Entrez Gene: ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=506| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Maguire D, Shah J, McCabe M |title=Assaying ATP synthase rotor activity. |journal=Adv. Exp. Med. Biol. |volume=578 |issue= |pages= 67–72 |year= 2007 |pmid= 16927672 |doi=
*cite journal | author=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317–20 |year= 1992 |pmid= 1602151 |doi=
*cite journal | author=Neckelmann N, Warner CK, Chung A, "et al." |title=The human ATP synthase beta subunit gene: sequence analysis, chromosome assignment, and differential expression. |journal=Genomics |volume=5 |issue= 4 |pages= 829–43 |year= 1990 |pmid= 2687158 |doi=
*cite journal | author=Ohta S, Kagawa Y |title=Human F1-ATPase: molecular cloning of cDNA for the beta subunit. |journal=J. Biochem. |volume=99 |issue= 1 |pages= 135–41 |year= 1986 |pmid= 2870059 |doi=
*cite journal | author=Wallace DC, Ye JH, Neckelmann SN, "et al." |title=Sequence analysis of cDNAs for the human and bovine ATP synthase beta subunit: mitochondrial DNA genes sustain seventeen times more mutations. |journal=Curr. Genet. |volume=12 |issue= 2 |pages= 81–90 |year= 1988 |pmid= 2896550 |doi=
*cite journal | author=Ohta S, Tomura H, Matsuda K, Kagawa Y |title=Gene structure of the human mitochondrial adenosine triphosphate synthase beta subunit. |journal=J. Biol. Chem. |volume=263 |issue= 23 |pages= 11257–62 |year= 1988 |pmid= 2900241 |doi=
*cite journal | author=Villena JA, Martin I, Viñas O, "et al." |title=ETS transcription factors regulate the expression of the gene for the human mitochondrial ATP synthase beta-subunit. |journal=J. Biol. Chem. |volume=269 |issue= 51 |pages= 32649–54 |year= 1995 |pmid= 7798271 |doi=
*cite journal | author=Abrahams JP, Leslie AG, Lutter R, Walker JE |title=Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria. |journal=Nature |volume=370 |issue= 6491 |pages= 621–8 |year= 1994 |pmid= 8065448 |doi= 10.1038/370621a0
*cite journal | author=Elston T, Wang H, Oster G |title=Energy transduction in ATP synthase. |journal=Nature |volume=391 |issue= 6666 |pages= 510–3 |year= 1998 |pmid= 9461222 |doi= 10.1038/35185
*cite journal | author=Wang H, Oster G |title=Energy transduction in the F1 motor of ATP synthase. |journal=Nature |volume=396 |issue= 6708 |pages= 279–82 |year= 1998 |pmid= 9834036 |doi= 10.1038/24409
*cite journal | author=Moser TL, Stack MS, Asplin I, "et al." |title=Angiostatin binds ATP synthase on the surface of human endothelial cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 6 |pages= 2811–6 |year= 1999 |pmid= 10077593 |doi=
*cite journal | author=Wang ZG, White PS, Ackerman SH |title=Atp11p and Atp12p are assembly factors for the F(1)-ATPase in human mitochondria. |journal=J. Biol. Chem. |volume=276 |issue= 33 |pages= 30773–8 |year= 2001 |pmid= 11410595 |doi= 10.1074/jbc.M104133200
*cite journal | author=Andersen JS, Lyon CE, Fox AH, "et al." |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=
*cite journal | author=Ackerman SH |title=Atp11p and Atp12p are chaperones for F(1)-ATPase biogenesis in mitochondria. |journal=Biochim. Biophys. Acta |volume=1555 |issue= 1-3 |pages= 101–5 |year= 2002 |pmid= 12206899 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Martinez LO, Jacquet S, Esteve JP, "et al." |title=Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis. |journal=Nature |volume=421 |issue= 6918 |pages= 75–9 |year= 2003 |pmid= 12511957 |doi= 10.1038/nature01250
*cite journal | author=Reuter TY, Medhurst AL, Waisfisz Q, "et al." |title=Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. |journal=Exp. Cell Res. |volume=289 |issue= 2 |pages= 211–21 |year= 2003 |pmid= 14499622 |doi=
*cite journal | author=Cross RL |title=Molecular motors: turning the ATP motor. |journal=Nature |volume=427 |issue= 6973 |pages= 407–8 |year= 2004 |pmid= 14749816 |doi= 10.1038/427407b
*cite journal | author=Aboulaich N, Vainonen JP, Strålfors P, Vener AV |title=Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes. |journal=Biochem. J. |volume=383 |issue= Pt 2 |pages= 237–48 |year= 2005 |pmid= 15242332 |doi= 10.1042/BJ20040647
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051PBB_Controls
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