MCM5

MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae), also known as MCM5, is a human gene.cite web | title = Entrez Gene: MCM5 MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4174| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.cite web | title = Entrez Gene: MCM5 MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4174| accessdate = ]

ee also

*Mini Chromosome Maintenance

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Burkhart R, Schulte D, Hu D, "et al." |title=Interactions of human nuclear proteins P1Mcm3 and P1Cdc46. |journal=Eur. J. Biochem. |volume=228 |issue= 2 |pages= 431–8 |year= 1995 |pmid= 7705359 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Hu B, Burkhart R, Schulte D, "et al." |title=The P1 family: a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins. |journal=Nucleic Acids Res. |volume=21 |issue= 23 |pages= 5289–93 |year= 1994 |pmid= 8265339 |doi=
*cite journal | author=Paul R, Hu B, Musahl C, "et al." |title=Coding sequence and chromosome mapping of the human gene (CDC46) for replication protein hCdc46/Mcm5. |journal=Cytogenet. Cell Genet. |volume=73 |issue= 4 |pages= 317–21 |year= 1996 |pmid= 8751386 |doi=
*cite journal | author=Ishimi Y, Ichinose S, Omori A, "et al." |title=Binding of human minichromosome maintenance proteins with histone H3. |journal=J. Biol. Chem. |volume=271 |issue= 39 |pages= 24115–22 |year= 1996 |pmid= 8798650 |doi=
*cite journal | author=Fujita M, Kiyono T, Hayashi Y, Ishibashi M |title=In vivo interaction of human MCM heterohexameric complexes with chromatin. Possible involvement of ATP. |journal=J. Biol. Chem. |volume=272 |issue= 16 |pages= 10928–35 |year= 1997 |pmid= 9099751 |doi=
*cite journal | author=Tsuruga H, Yabuta N, Hashizume K, "et al." |title=Expression, nuclear localization and interactions of human MCM/P1 proteins. |journal=Biochem. Biophys. Res. Commun. |volume=236 |issue= 1 |pages= 118–25 |year= 1997 |pmid= 9223437 |doi= 10.1006/bbrc.1997.6865
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Zhang JJ, Zhao Y, Chait BT, "et al." |title=Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation. |journal=EMBO J. |volume=17 |issue= 23 |pages= 6963–71 |year= 1999 |pmid= 9843502 |doi= 10.1093/emboj/17.23.6963
*cite journal | author=Ohtani K, Iwanaga R, Nakamura M, "et al." |title=Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F. |journal=Oncogene |volume=18 |issue= 14 |pages= 2299–309 |year= 1999 |pmid= 10327050 |doi= 10.1038/sj.onc.1202544
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=DaFonseca CJ, Shu F, Zhang JJ |title=Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 6 |pages= 3034–9 |year= 2001 |pmid= 11248027 |doi= 10.1073/pnas.061487598
*cite journal | author=Going JJ, Keith WN, Neilson L, "et al." |title=Aberrant expression of minichromosome maintenance proteins 2 and 5, and Ki-67 in dysplastic squamous oesophageal epithelium and Barrett's mucosa. |journal=Gut |volume=50 |issue= 3 |pages= 373–7 |year= 2002 |pmid= 11839717 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kneissl M, Pütter V, Szalay AA, Grummt F |title=Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. |journal=J. Mol. Biol. |volume=327 |issue= 1 |pages= 111–28 |year= 2003 |pmid= 12614612 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Bouwmeester T, Bauch A, Ruffner H, "et al." |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086
*cite journal | author=Ramachandran N, Hainsworth E, Bhullar B, "et al." |title=Self-assembling protein microarrays. |journal=Science |volume=305 |issue= 5680 |pages= 86–90 |year= 2004 |pmid= 15232106 |doi= 10.1126/science.1097639
*cite journal | author=Yu Z, Feng D, Liang C |title=Pairwise interactions of the six human MCM protein subunits. |journal=J. Mol. Biol. |volume=340 |issue= 5 |pages= 1197–206 |year= 2004 |pmid= 15236977 |doi= 10.1016/j.jmb.2004.05.024
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051

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