C-fos induced growth factor

C-fos induced growth factor (FIGF) (or vascular endothelial growth factor D) is a vascular endothelial growth factor. FIGF is also its human gene.cite web | title = Entrez Gene: FIGF c-fos induced growth factor (vascular endothelial growth factor D)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2277| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.cite web | title = Entrez Gene: FIGF c-fos induced growth factor (vascular endothelial growth factor D)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2277| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Orlandini M, Marconcini L, Ferruzzi R, Oliviero S |title=Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 21 |pages= 11675–80 |year= 1996 |pmid= 8876195 |doi=
*cite journal | author=Yamada Y, Nezu J, Shimane M, Hirata Y |title=Molecular cloning of a novel vascular endothelial growth factor, VEGF-D. |journal=Genomics |volume=42 |issue= 3 |pages= 483–8 |year= 1997 |pmid= 9205122 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Achen MG, Jeltsch M, Kukk E, "et al." |title=Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4). |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 2 |pages= 548–53 |year= 1998 |pmid= 9435229 |doi=
*cite journal | author=Rocchigiani M, Lestingi M, Luddi A, "et al." |title=Human FIGF: cloning, gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes. |journal=Genomics |volume=47 |issue= 2 |pages= 207–16 |year= 1998 |pmid= 9479493 |doi= 10.1006/geno.1997.5079
*cite journal | author=Stacker SA, Stenvers K, Caesar C, "et al." |title=Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers. |journal=J. Biol. Chem. |volume=274 |issue= 45 |pages= 32127–36 |year= 1999 |pmid= 10542248 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Nakamura Y, Yasuoka H, Tsujimoto M, "et al." |title=Prognostic significance of vascular endothelial growth factor D in breast carcinoma with long-term follow-up. |journal=Clin. Cancer Res. |volume=9 |issue= 2 |pages= 716–21 |year= 2003 |pmid= 12576440 |doi=
*cite journal | author=Yokoyama Y, Charnock-Jones DS, Licence D, "et al." |title=Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma. |journal=Br. J. Cancer |volume=88 |issue= 2 |pages= 237–44 |year= 2003 |pmid= 12610509 |doi= 10.1038/sj.bjc.6600701
*cite journal | author=Rissanen TT, Markkanen JE, Gruchala M, "et al." |title=VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses. |journal=Circ. Res. |volume=92 |issue= 10 |pages= 1098–106 |year= 2003 |pmid= 12714562 |doi= 10.1161/01.RES.0000073584.46059.E3
*cite journal | author=Funaki H, Nishimura G, Harada S, "et al." |title=Expression of vascular endothelial growth factor D is associated with lymph node metastasis in human colorectal carcinoma. |journal=Oncology |volume=64 |issue= 4 |pages= 416–22 |year= 2003 |pmid= 12759540 |doi= 10.1159/000070301
*cite journal | author=Orlandini M, Semboloni S, Oliviero S |title=Beta-catenin inversely regulates vascular endothelial growth factor-D mRNA stability. |journal=J. Biol. Chem. |volume=278 |issue= 45 |pages= 44650–6 |year= 2004 |pmid= 12920128 |doi= 10.1074/jbc.M304255200
*cite journal | author=McColl BK, Baldwin ME, Roufail S, "et al." |title=Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D. |journal=J. Exp. Med. |volume=198 |issue= 6 |pages= 863–8 |year= 2003 |pmid= 12963694 |doi= 10.1084/jem.20030361
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Vlahakis NE, Young BA, Atakilit A, Sheppard D |title=The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1. |journal=J. Biol. Chem. |volume=280 |issue= 6 |pages= 4544–52 |year= 2005 |pmid= 15590642 |doi= 10.1074/jbc.M412816200
*cite journal | author=Kurahara H, Takao S, Maemura K, "et al." |title=Impact of vascular endothelial growth factor-C and -D expression in human pancreatic cancer: its relationship to lymph node metastasis. |journal=Clin. Cancer Res. |volume=10 |issue= 24 |pages= 8413–20 |year= 2005 |pmid= 15623620 |doi= 10.1158/1078-0432.CCR-04-0379
*cite journal | author=Fink AM, Kaltenegger I, Schneider B, "et al." |title=Serum level of VEGF-D in patients with primary lymphedema. |journal=Lymphology |volume=37 |issue= 4 |pages= 185–9 |year= 2005 |pmid= 15693535 |doi=
*cite journal | author=Kaushal V, Mukunyadzi P, Dennis RA, "et al." |title=Stage-specific characterization of the vascular endothelial growth factor axis in prostate cancer: expression of lymphangiogenic markers is associated with advanced-stage disease. |journal=Clin. Cancer Res. |volume=11 |issue= 2 Pt 1 |pages= 584–93 |year= 2005 |pmid= 15701844 |doi=
*cite journal | author=Yasuoka H, Nakamura Y, Zuo H, "et al." |title=VEGF-D expression and lymph vessels play an important role for lymph node metastasis in papillary thyroid carcinoma. |journal=Mod. Pathol. |volume=18 |issue= 8 |pages= 1127–33 |year= 2005 |pmid= 15803188 |doi= 10.1038/modpathol.3800402

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