RAD52

RAD52

RAD52 homolog (S. cerevisiae), also known as RAD52, is a human gene.cite web | title = Entrez Gene: RAD52 RAD52 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5893| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.cite web | title = Entrez Gene: RAD52 RAD52 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5893| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Muris DF, Bezzubova O, Buerstedde JM, "et al." |title=Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination. |journal=Mutat. Res. |volume=315 |issue= 3 |pages= 295–305 |year= 1994 |pmid= 7526206 |doi=
*cite journal | author=Shen Z, Denison K, Lobb R, "et al." |title=The human and mouse homologs of the yeast RAD52 gene: cDNA cloning, sequence analysis, assignment to human chromosome 12p12.2-p13, and mRNA expression in mouse tissues. |journal=Genomics |volume=25 |issue= 1 |pages= 199–206 |year= 1995 |pmid= 7774919 |doi=
*cite journal | author=Park MS |title=Expression of human RAD52 confers resistance to ionizing radiation in mammalian cells. |journal=J. Biol. Chem. |volume=270 |issue= 26 |pages= 15467–70 |year= 1995 |pmid= 7797537 |doi=
*cite journal | author=Shen Z, Pardington-Purtymun PE, Comeaux JC, "et al." |title=UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins. |journal=Genomics |volume=36 |issue= 2 |pages= 271–9 |year= 1997 |pmid= 8812453 |doi= 10.1006/geno.1996.0462
*cite journal | author=Shen Z, Pardington-Purtymun PE, Comeaux JC, "et al." |title=Associations of UBE2I with RAD52, UBL1, p53, and RAD51 proteins in a yeast two-hybrid system. |journal=Genomics |volume=37 |issue= 2 |pages= 183–6 |year= 1997 |pmid= 8921390 |doi= 10.1006/geno.1996.0540
*cite journal | author=Chen G, Yuan SS, Liu W, "et al." |title=Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl. |journal=J. Biol. Chem. |volume=274 |issue= 18 |pages= 12748–52 |year= 1999 |pmid= 10212258 |doi=
*cite journal | author=Kito K, Wada H, Yeh ET, Kamitani T |title=Identification of novel isoforms of human RAD52. |journal=Biochim. Biophys. Acta |volume=1489 |issue= 2-3 |pages= 303–14 |year= 2000 |pmid= 10673031 |doi=
*cite journal | author=Stasiak AZ, Larquet E, Stasiak A, "et al." |title=The human Rad52 protein exists as a heptameric ring. |journal=Curr. Biol. |volume=10 |issue= 6 |pages= 337–40 |year= 2000 |pmid= 10744977 |doi=
*cite journal | author=Parsons CA, Baumann P, Van Dyck E, West SC |title=Precise binding of single-stranded DNA termini by human RAD52 protein. |journal=EMBO J. |volume=19 |issue= 15 |pages= 4175–81 |year= 2000 |pmid= 10921897 |doi= 10.1093/emboj/19.15.4175
*cite journal | author=Mer G, Bochkarev A, Gupta R, "et al." |title=Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA. |journal=Cell |volume=103 |issue= 3 |pages= 449–56 |year= 2000 |pmid= 11081631 |doi=
*cite journal | author=Ranatunga W, Jackson D, Flowers II RA, Borgstahl GE |title=Human RAD52 protein has extreme thermal stability. |journal=Biochemistry |volume=40 |issue= 29 |pages= 8557–62 |year= 2001 |pmid= 11456495 |doi=
*cite journal | author=Van Dyck E, Stasiak AZ, Stasiak A, West SC |title=Visualization of recombination intermediates produced by RAD52-mediated single-strand annealing. |journal=EMBO Rep. |volume=2 |issue= 10 |pages= 905–9 |year= 2002 |pmid= 11571269 |doi= 10.1093/embo-reports/kve201
*cite journal | author=Kim PM, Allen C, Wagener BM, "et al." |title=Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells. |journal=Nucleic Acids Res. |volume=29 |issue= 21 |pages= 4352–60 |year= 2001 |pmid= 11691922 |doi=
*cite journal | author=Yáñez RJ, Porter AC |title=Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line. |journal=Nucleic Acids Res. |volume=30 |issue= 3 |pages= 740–8 |year= 2002 |pmid= 11809887 |doi=
*cite journal | author=Jackson D, Dhar K, Wahl JK, "et al." |title=Analysis of the human replication protein A:Rad52 complex: evidence for crosstalk between RPA32, RPA70, Rad52 and DNA. |journal=J. Mol. Biol. |volume=321 |issue= 1 |pages= 133–48 |year= 2002 |pmid= 12139939 |doi=
*cite journal | author=Kagawa W, Kurumizaka H, Ishitani R, "et al." |title=Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form. |journal=Mol. Cell |volume=10 |issue= 2 |pages= 359–71 |year= 2002 |pmid= 12191481 |doi=
*cite journal | author=Singleton MR, Wentzell LM, Liu Y, "et al." |title=Structure of the single-strand annealing domain of human RAD52 protein. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 21 |pages= 13492–7 |year= 2002 |pmid= 12370410 |doi= 10.1073/pnas.212449899
*cite journal | author=Liu J, Meng X, Shen Z |title=Association of human RAD52 protein with transcription factors. |journal=Biochem. Biophys. Res. Commun. |volume=297 |issue= 5 |pages= 1191–6 |year= 2002 |pmid= 12372413 |doi=
*cite journal | author=Han J, Hankinson SE, De Vivo I, "et al." |title=No association between a stop codon polymorphism in RAD52 and breast cancer risk. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=11 |issue= 10 Pt 1 |pages= 1138–9 |year= 2002 |pmid= 12376524 |doi=
*cite journal | author=Kitao H, Yuan ZM |title=Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation. |journal=J. Biol. Chem. |volume=277 |issue= 50 |pages= 48944–8 |year= 2003 |pmid= 12379650 |doi= 10.1074/jbc.M208151200

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • DNA repair and recombination protein RAD54-like — RAD54 like (S. cerevisiae) Identifiers Symbols RAD54L; HR54; RAD54A; hHR54; hRAD54 External IDs …   Wikipedia

  • SUMO network — consists of enzymes and substrates involved in the dynamic posttranslational modification process of sumoylation (i.e. transfer of SUMO protein to substrates). Network membersThe SUMO network members (gene name and aliases) as published in the… …   Wikipedia

  • Small ubiquitin-related modifier 1 — SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), also known as SUMO1, is a human gene. PBB Summary section title = summary text = This gene encodes a protein that is a member of the SUMO (small ubiquitin like modifier) protein family. It… …   Wikipedia

  • Nicotinamide adenine dinucleotide — Nicotinamide adenine dinucleotide …   Wikipedia

  • Crystal system — Diamond crystal structure consists of face centered cubic lattice. In crystallography, the terms crystal system, crystal family, and lattice system each refer to one of several classes of space groups, lattices, point groups, or crystals.… …   Wikipedia

  • DNA-binding protein — Cro protein complex with DNA Interaction of DNA (shown in …   Wikipedia

  • Homologous recombination — Figure 1. During meiosis, homologous recombination can produce new combinations of genes as shown here between similar but not identical copies of human chromosome 1. Homologous recombination is a type of genetic recombination in which nucleotide …   Wikipedia

  • RAD51 — is a human gene. The protein encoded by this gene is a member of the RAD51 protein family which assist in repair of DNA double strand breaks. RAD51 family members are highly similar to the bacterial RecA and yeast Rad51. The protein is highly… …   Wikipedia

  • Postreplication repair — is the repair of damage to the DNA that takes place after replication. Some example genes in humans include: BRCA2 and BRCA1 BLM NBS1 DNA damage prevents the normal enzymatic synthesis of DNA by the replication fork.[1][2][3][4] …   Wikipedia

  • UBE2I — Ubiquitin conjugating enzyme E2I (UBC9 homolog, yeast), also known as UBE2I, is a human gene. PBB Summary section title = summary text = The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”