FSHB

FSHB

Follicle stimulating hormone, beta polypeptide, also known as FSHB, is a human gene.cite web | title = Entrez Gene: FSHB follicle stimulating hormone, beta polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2488| accessdate = ]

PBB_Summary
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summary_text = The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. All of these glycoproteins consist of an identical alpha subunit and a hormone-specific beta subunit. This gene encodes the beta subunit of follicle-stimulating hormone. In conjunction with luteinizing hormone, follicle-stimulating hormone induces egg and sperm production. Alternative splicing results in two transcript variants encoding the same protein.cite web | title = Entrez Gene: FSHB follicle stimulating hormone, beta polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2488| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Barrios-De-Tomasi J, Timossi C, Merchant H, "et al." |title=Assessment of the in vitro and in vivo biological activities of the human follicle-stimulating isohormones. |journal=Mol. Cell. Endocrinol. |volume=186 |issue= 2 |pages= 189–98 |year= 2002 |pmid= 11900895 |doi=
*cite journal | author=Saxena BB, Rathnam P |title=Amino acid sequence of the beta subunit of follicle-stimulating hormone from human pituitary glands. |journal=J. Biol. Chem. |volume=251 |issue= 4 |pages= 993–1005 |year= 1976 |pmid= 1249074 |doi=
*cite journal | author=Keene JL, Matzuk MM, Otani T, "et al." |title=Expression of biologically active human follitropin in Chinese hamster ovary cells. |journal=J. Biol. Chem. |volume=264 |issue= 9 |pages= 4769–75 |year= 1989 |pmid= 2494176 |doi=
*cite journal | author=Watkins PC, Eddy R, Beck AK, "et al." |title=DNA sequence and regional assignment of the human follicle-stimulating hormone beta-subunit gene to the short arm of human chromosome 11. |journal=DNA |volume=6 |issue= 3 |pages= 205–12 |year= 1987 |pmid= 2885163 |doi=
*cite journal | author=Jameson JL, Becker CB, Lindell CM, Habener JF |title=Human follicle-stimulating hormone beta-subunit gene encodes multiple messenger ribonucleic acids. |journal=Mol. Endocrinol. |volume=2 |issue= 9 |pages= 806–15 |year= 1988 |pmid= 3139991 |doi=
*cite journal | author=Shome B, Parlow AF, Liu WK, "et al." |title=A reevaluation of the amino acid sequence of human follitropin beta-subunit. |journal=J. Protein Chem. |volume=7 |issue= 4 |pages= 325–39 |year= 1989 |pmid= 3151250 |doi=
*cite journal | author=Shome B, Parlow AF |title=Human follicle stimulating hormone: first proposal for the amino acid sequence of the hormone-specific, beta subunit (hFSHb). |journal=J. Clin. Endocrinol. Metab. |volume=39 |issue= 1 |pages= 203–5 |year= 1974 |pmid= 4835136 |doi=
*cite journal | author=Fujiki Y, Rathnam P, Saxena BB |title=Studies on the disulfide bonds in human pituitary follicle-stimulating hormone. |journal=Biochim. Biophys. Acta |volume=624 |issue= 2 |pages= 428–35 |year= 1980 |pmid= 6774759 |doi=
*cite journal | author=Böckers TM, Nieschlag E, Kreutz MR, Bergmann M |title=Localization of follicle-stimulating hormone (FSH) immunoreactivity and hormone receptor mRNA in testicular tissue of infertile men. |journal=Cell Tissue Res. |volume=278 |issue= 3 |pages= 595–600 |year= 1995 |pmid= 7850869 |doi=
*cite journal | author=Matthews CH, Borgato S, Beck-Peccoz P, "et al." |title=Primary amenorrhoea and infertility due to a mutation in the beta-subunit of follicle-stimulating hormone. |journal=Nat. Genet. |volume=5 |issue= 1 |pages= 83–6 |year= 1993 |pmid= 8220432 |doi= 10.1038/ng0993-83
*cite journal | author=Layman LC, Lee EJ, Peak DB, "et al." |title=Delayed puberty and hypogonadism caused by mutations in the follicle-stimulating hormone beta-subunit gene. |journal=N. Engl. J. Med. |volume=337 |issue= 9 |pages= 607–11 |year= 1997 |pmid= 9271483 |doi=
*cite journal | author=Cargill M, Altshuler D, Ireland J, "et al." |title=Characterization of single-nucleotide polymorphisms in coding regions of human genes. |journal=Nat. Genet. |volume=22 |issue= 3 |pages= 231–8 |year= 1999 |pmid= 10391209 |doi= 10.1038/10290
*cite journal | author=Grasso P, Rozhavskaya-Arena M, Reichert LE |title=Cysteine residues in a synthetic peptide corresponding to human follicle-stimulating hormone beta-subunit receptor-binding domain 81-95 [hFSH-beta-(81-95)] modulate the in vivo effects of hFSH-beta-(81-95) on the mouse estrous cycle. |journal=Regul. Pept. |volume=81 |issue= 1-3 |pages= 67–71 |year= 1999 |pmid= 10395410 |doi=
*cite journal | author=Ben-Menahem D, Hyde R, Pixley M, "et al." |title=Synthesis of multi-subunit domain gonadotropin complexes: a model for alpha/beta heterodimer formation. |journal=Biochemistry |volume=38 |issue= 46 |pages= 15070–7 |year= 1999 |pmid= 10563789 |doi=
*cite journal | author=Dias Neto E, Correa RG, Verjovski-Almeida S, "et al." |title=Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 7 |pages= 3491–6 |year= 2000 |pmid= 10737800 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Fox KM, Dias JA, Van Roey P |title=Three-dimensional structure of human follicle-stimulating hormone. |journal=Mol. Endocrinol. |volume=15 |issue= 3 |pages= 378–89 |year= 2001 |pmid= 11222739 |doi=
*cite journal | author=Amoresano A, Orrù S, Siciliano RA, "et al." |title=Assignment of the complete disulphide bridge pattern in the human recombinant follitropin beta-chain. |journal=Biol. Chem. |volume=382 |issue= 6 |pages= 961–8 |year= 2002 |pmid= 11501762 |doi=
*cite journal | author=Walton WJ, Nguyen VT, Butnev VY, "et al." |title=Characterization of human FSH isoforms reveals a nonglycosylated beta-subunit in addition to the conventional glycosylated beta-subunit. |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue= 8 |pages= 3675–85 |year= 2001 |pmid= 11502795 |doi=

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