Interferon gamma receptor 1

Interferon gamma receptor 1

Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a human gene.cite web | title = Entrez Gene: IFNGR1 interferon gamma receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3459| accessdate = ]

PBB_Summary
section_title =
summary_text = IFNGR1 encodes the ligand-binding chain (alpha) of the heterodimeric gamma interferon receptor, which is found on macrophages. IFNGR2 encodes the non-ligand-binding partner of the heterodimeric receptor.cite web | title = Entrez Gene: IFNGR1 interferon gamma receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3459| accessdate = ]

ee also

* Cluster of differentiation
* Interferon-gamma receptor

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Samuel CE |title=Antiviral actions of interferons. |journal=Clin. Microbiol. Rev. |volume=14 |issue= 4 |pages= 778–809, table of contents |year= 2002 |pmid= 11585785 |doi= 10.1128/CMR.14.4.778-809.2001
*cite journal | author=van Loon AP, Ozmen L, Fountoulakis M, "et al." |title=High-affinity receptor for interferon-gamma (IFN-gamma), a ubiquitous protein occurring in different molecular forms on human cells: blood monocytes and eleven different cell lines have the same IFN-gamma receptor protein. |journal=J. Leukoc. Biol. |volume=49 |issue= 5 |pages= 462–73 |year= 1991 |pmid= 1826725 |doi=
*cite journal | author=Le Coniat M, Alcaide-Loridan C, Fellous M, Berger R |title=Human interferon gamma receptor 1 (IFNGR1) gene maps to chromosome region 6q23-6q24. |journal=Hum. Genet. |volume=84 |issue= 1 |pages= 92–4 |year= 1990 |pmid= 2532616 |doi=
*cite journal | author=Novick D, Orchansky P, Revel M, Rubinstein M |title=The human interferon-gamma receptor. Purification, characterization, and preparation of antibodies. |journal=J. Biol. Chem. |volume=262 |issue= 18 |pages= 8483–7 |year= 1987 |pmid= 2954953 |doi=
*cite journal | author=Aguet M, Dembić Z, Merlin G |title=Molecular cloning and expression of the human interferon-gamma receptor. |journal=Cell |volume=55 |issue= 2 |pages= 273–80 |year= 1988 |pmid= 2971451 |doi=
*cite journal | author=Szente BE, Subramaniam PS, Johnson HM |title=Identification of IFN-gamma receptor binding sites for JAK2 and enhancement of binding by IFN-gamma and its C-terminal peptide IFN-gamma(95-133). |journal=J. Immunol. |volume=155 |issue= 12 |pages= 5617–22 |year= 1996 |pmid= 7499845 |doi=
*cite journal | author=Igarashi K, Garotta G, Ozmen L, "et al." |title=Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor. |journal=J. Biol. Chem. |volume=269 |issue= 20 |pages= 14333–6 |year= 1994 |pmid= 7514165 |doi=
*cite journal | author=Walter MR, Windsor WT, Nagabhushan TL, "et al." |title=Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor. |journal=Nature |volume=376 |issue= 6537 |pages= 230–5 |year= 1995 |pmid= 7617032 |doi= 10.1038/376230a0
*cite journal | author=Kotenko SV, Izotova LS, Pollack BP, "et al." |title=Interaction between the components of the interferon gamma receptor complex. |journal=J. Biol. Chem. |volume=270 |issue= 36 |pages= 20915–21 |year= 1995 |pmid= 7673114 |doi=
*cite journal |author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Tjoelker LW, Seyfried CE, Eddy RL, "et al." |title=Human, mouse, and rat calnexin cDNA cloning: identification of potential calcium binding motifs and gene localization to human chromosome 5. |journal=Biochemistry |volume=33 |issue= 11 |pages= 3229–36 |year= 1994 |pmid= 8136357 |doi=
*cite journal | author=Greenlund AC, Farrar MA, Viviano BL, Schreiber RD |title=Ligand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). |journal=EMBO J. |volume=13 |issue= 7 |pages= 1591–600 |year= 1994 |pmid= 8156998 |doi=
*cite journal | author=Stüber D, Friedlein A, Fountoulakis M, "et al." |title=Alignment of disulfide bonds of the extracellular domain of the interferon gamma receptor and investigation of their role in biological activity. |journal=Biochemistry |volume=32 |issue= 9 |pages= 2423–30 |year= 1993 |pmid= 8443182 |doi=
*cite journal | author=Dalton DK, Pitts-Meek S, Keshav S, "et al." |title=Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. |journal=Science |volume=259 |issue= 5102 |pages= 1739–42 |year= 1993 |pmid= 8456300 |doi=
*cite journal | author=Novelli F, Giovarelli M, Gentz R, "et al." |title=Modulation of interferon-gamma receptor during human T lymphocyte alloactivation. |journal=Eur. J. Immunol. |volume=23 |issue= 6 |pages= 1226–31 |year= 1993 |pmid= 8500521 |doi=
*cite journal | author=Newport MJ, Huxley CM, Huston S, "et al." |title=A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection. |journal=N. Engl. J. Med. |volume=335 |issue= 26 |pages= 1941–9 |year= 1997 |pmid= 8960473 |doi=
*cite journal | author=Jouanguy E, Altare F, Lamhamedi S, "et al." |title=Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guérin infection. |journal=N. Engl. J. Med. |volume=335 |issue= 26 |pages= 1956–61 |year= 1997 |pmid= 8960475 |doi=
*cite journal | author=Gerritsma JS, Gerritsen AF, De Ley M, "et al." |title=Interferon-gamma induces biosynthesis of complement components C2, C4 and factor H by human proximal tubular epithelial cells. |journal=Cytokine |volume=9 |issue= 4 |pages= 276–83 |year= 1997 |pmid= 9112336 |doi= 10.1006/cyto.1996.0164
*cite journal | author=Sogabe S, Stuart F, Henke C, "et al." |title=Neutralizing epitopes on the extracellular interferon gamma receptor (IFNgammaR) alpha-chain characterized by homolog scanning mutagenesis and X-ray crystal structure of the A6 fab-IFNgammaR1-108 complex. |journal=J. Mol. Biol. |volume=273 |issue= 4 |pages= 882–97 |year= 1998 |pmid= 9367779 |doi= 10.1006/jmbi.1997.1336
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=

External links

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