CorA metal ion transporter

CorA-like Mg2+ transporter protein
Structure of the CorA Mg2+ transporter.[1]
Identifiers
Symbol	CorA
Pfam	PF01544
InterPro	IPR002523
TCDB	1.A.35
OPM family	72
OPM protein	2bbj
Available protein structures: Pfam structures PDB RCSB PDB; PDBe PDBsum structure summary

The CorA transport system is the primary Mg²⁺ influx system of Salmonella typhimurium and Escherichia coli^[2][3]. CorA is ubiquitous in the Bacteria and Archaea. There are also eukaryotic members of the family.

Subfamilies

• Magnesium and cobalt transport protein CorA IPR004488

Human proteins containing this domain

MRS2L;

References

1. ^ Lunin VV, Dobrovetsky E, Khutoreskaya G, et al. (April 2006). "Crystal structure of the CorA Mg2+ transporter". Nature 440 (7085): 833–7. doi:10.1038/nature04642. PMID 16598263. 
2. ^ Maguire ME, Kehres DG, Lawyer CH (1998). "The CorA magnesium transporter gene family". Microb. Comp. Genomics 3 (3): 151–169. doi:10.1089/omi.1.1998.3.151. PMID 9775386. 
3. ^ Smith RL, Maguire ME, Szegedy MA, Kucharski LM, Walker C, Wiet RM, Redpath A, Kaczmarek MT (1998). "The CorA Mg2+ transport protein of Salmonella typhimurium. Mutagenesis of conserved residues in the third membrane domain identifies a Mg2+ pore". J. Biol. Chem. 273 (44): 28663–28669. doi:10.1074/jbc.273.44.28663. PMID 9786860. 

Further reading

• Kehres DG, Lawyer CH, Maguire ME (1998). "The CorA magnesium transporter gene family". Microb. Comp. Genomics 3 (3): 151–69. doi:10.1089/omi.1.1998.3.151. PMID 9775386. 
• Smith RL, Szegedy MA, Kucharski LM, et al. (October 1998). "The CorA Mg2+ transport protein of Salmonella typhimurium. Mutagenesis of conserved residues in the third membrane domain identifies a Mg2+ pore". J. Biol. Chem. 273 (44): 28663–9. doi:10.1074/jbc.273.44.28663. PMID 9786860. 
• Wiesenberger G, Waldherr M, Schweyen RJ (April 1992). "The nuclear gene MRS2 is essential for the excision of group II introns from yeast mitochondrial transcripts in vivo". J. Biol. Chem. 267 (10): 6963–9. PMID 1551905. 

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