UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase

In enzymology, an UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase (EC number|2.7.8.17) is an enzyme that catalyzes the chemical reaction

:UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose $ightleftharpoons$ UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose

Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and lysosomal-enzyme D-mannose, whereas its two products are UMP and lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups transferases for other substituted phosphate groups. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase. Other names in common use include UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase, UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase, uridine diphosphoacetylglucosamine-lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase, uridine diphosphoacetylglucosamine-glycoprotein acetylglucosamine-1-phosphotransferase, lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase, UDP-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase, UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase, UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase, and UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-1-phosphotransferase.

References

*
*
*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|84012-69-1."

Gene Ontology (GO) codes