Opheline kinase

Opheline kinase
opheline kinase
Identifiers
EC number 2.7.3.7
CAS number 37278-15-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an opheline kinase (EC 2.7.3.7) is an enzyme that catalyzes the chemical reaction

ATP + guanidinoethyl methyl phosphate \rightleftharpoons ADP + N'-phosphoguanidinoethyl methylphosphate

Thus, the two substrates of this enzyme are ATP and guanidinoethyl methyl phosphate, whereas its two products are ADP and N'-phosphoguanidinoethyl methylphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP:guanidinoethyl-methyl-phosphate phosphotransferase.

References

  • Thoai NV, di Jeso F, Robin Y and der Terrossian E (1966). "Sur la nouvelle acide adenosine 5'-triphosphorique:guanidine phosphotransferase, l'opheline kinase". Biochim. Biophys. Acta 113: 542–550.