Diphosphate-fructose-6-phosphate 1-phosphotransferase

In enzymology, a diphosphate-fructose-6-phosphate 1-phosphotransferase (EC number|2.7.1.90) is an enzyme that catalyzes the chemical reaction

:diphosphate + D-fructose 6-phosphate $ightleftharpoons$ phosphate + D-fructose 1,6-bisphosphate

Thus, the two substrates of this enzyme are diphosphate and D-fructose 6-phosphate, whereas its two products are phosphate and D-fructose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is diphosphate:D-fructose-6-phosphate 1-phosphotransferase. Other names in common use include 6-phosphofructokinase (pyrophosphate), pyrophosphate-fructose 6-phosphate 1-phosphotransferase, inorganic pyrophosphate-dependent phosphofructokinase, inorganic pyrophosphate-phosphofructokinase, pyrophosphate-dependent phosphofructo-1-kinase, and pyrophosphate-fructose 6-phosphate phosphotransferase. This enzyme participates in fructose and mannose metabolism.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1KZH and PDB link|2F48.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|55326-40-4."

Gene Ontology (GO) codes