N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase

N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase
N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase
Identifiers
EC number 2.4.1.188
CAS number 118731-83-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase (EC 2.4.1.188) is an enzyme that catalyzes the chemical reaction

UDP-glucose + N-acetyl-D-glucosaminyldiphosphoundecaprenol \rightleftharpoons UDP + beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol

Thus, the two substrates of this enzyme are UDP-glucose and N-acetyl-D-glucosaminyldiphosphoundecaprenol, whereas its two products are UDP and beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase. Other names in common use include UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol, glucosyltransferase, uridine, diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol, and glucosyltransferase.

References

  • Kumita K, Murazumi N, Araki Y, Ito E (Tokyo). "Solubilization and properties of UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase from Bacillus coagulans AHU 1366 membranes". J. Biochem. (6): 985–8. PMID 2977388. 
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