3T3-L1

3T3-L1

3T3-L1 is a cell line derived from 3T3 cells that is used in biological research on adipose tissue. 3T3-L1 cells have a fibroblast-like morphology, but, under appropriate conditions, the cells differentiate into an adipocyte-like phenotype.

3T3-L1 cells of the adipocyte morphology increase the synthesis and accumulation of triglycerides and acquire the signet ring appearance of adipose cells. These cells are also sensitive to lipogenic and lipolytic hormones and drugs, including epinephrine, isoproterenol, and insulin. [cite journal |author=Green H, Kehinde O |title=An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion |journal=Cell |volume=5 |issue=1 |pages=19–27 |year=1975 |pmid=165899 |doi=]

ources


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • 3T3 cells — NIH/3T3 Fibroblasts in cell culture 3T3 cells come from a cell line established in 1962 by two scientists then at the Department of Pathology in the New York University School of Medicine, George Todaro and Howard Green. The 3T3 cell line has… …   Wikipedia

  • NIH 3T3 cells — Very widely used mouse fibroblast cell line; 3T3 cells have been derived from different mouse strains and it is therefore important to define the particular cell line. NIH strain were from the National Institute of Health in the USA …   Dictionary of molecular biology

  • Swiss 3T3 cells — An immortal line of fibroblast like cells established from whole trypsinised embryos of Swiss mice (not an inbred stock) under conditions that favour establishment of cells with low saturation density in culture …   Dictionary of molecular biology

  • Phototoxicity — is a phenomenon known in live cell, where illuminating a fluorescent molecule (the fluorescently active site is called a fluorophore) causes the selective death of the cells expressing it. In fluorescence microscopyWhile not completely understood …   Wikipedia

  • Lignee cellulaire — Lignée cellulaire Une lignée cellulaire est une population homogène de cellules, stables après des mitoses successives, et ayant en théorie une capacité illimitée de division. Il s agit en général de cellules cancéreuses prélevées chez un patient …   Wikipédia en Français

  • Lignée Cellulaire — Une lignée cellulaire est une population homogène de cellules, stables après des mitoses successives, et ayant en théorie une capacité illimitée de division. Il s agit en général de cellules cancéreuses prélevées chez un patient (comme les… …   Wikipédia en Français

  • Cell culture — in a Petri dish Epithelial cells in culture, stained for keratin (red) an …   Wikipedia

  • Chemerin — Retinoic acid receptor responder (tazarotene induced) 2 Identifiers Symbols RARRES2; HP10433; TIG2 External IDs …   Wikipedia

  • Rho family of GTPases — The Rho family of GTPases is a family of small ( 21 kDa) signaling G protein (more specific, a GTPase), and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have been shown to regulate many aspects of intracellular… …   Wikipedia

  • MDM4 — Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse), also known as MDM4, is a human gene.cite web | title = Entrez Gene: MDM4 Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)| url =… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”