Discadenine synthase

Discadenine synthase
discadenine synthase
Identifiers
EC number 2.5.1.24
CAS number 74082-52-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a discadenine synthase (EC 2.5.1.24) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + N6-(Delta2-isopentenyl)-adenine \rightleftharpoons 5'-methylthioadenosine + discadenine

Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and N6-(Delta2-isopentenyl)-adenine, whereas its two products are 5'-methylthioadenosine and discadenine.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase. Other names in common use include discadenine synthetase, S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine, and 3-(3-amino-3-carboxypropyl)-transferase.

References

  • Taya Y, Tanaka Y, Nishimura S (1978). "Cell-free biosynthesis of discadenine, a spore germination inhibitor of Dictyostelium discoideum". FEBS. Lett. 89 (2): 326–8. doi:10.1016/0014-5793(78)80247-6. PMID 566219. 
This transferase article is a stub. You can help Wikipedia by expanding it.