2-hydroxy-3-oxoadipate synthase
- 2-hydroxy-3-oxoadipate synthase
In enzymology, a 2-hydroxy-3-oxoadipate synthase (EC number|2.2.1.5) is an enzyme that catalyzes the chemical reaction
:2-oxoglutarate + glyoxylate 2-hydroxy-3-oxoadipate + CO2
Thus, the two substrates of this enzyme are 2-oxoglutarate and glyoxylate, whereas its two products are 2-hydroxy-3-oxoadipate and CO2.
This enzyme belongs to the family of transferases, specifically those transferring aldehyde or ketonic groups (transaldolases and transketolases, respectively). The systematic name of this enzyme class is . Other names in common use include 2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating), alpha-ketoglutaric-glyoxylic carboligase, and oxoglutarate: glyoxylate carboligase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It employs one cofactor, thiamin diphosphate.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9054-72-2."
Gene Ontology (GO) codes
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