CCRL2

CCRL2

Chemokine (C-C motif) receptor-like 2, also known as CCRL2, is a human gene.cite web | title = Entrez Gene: CCRL2 chemokine (C-C motif) receptor-like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9034| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.cite web | title = Entrez Gene: CCRL2 chemokine (C-C motif) receptor-like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9034| accessdate = ]

References

Further reading

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citations =
*cite journal | author=Daugherty BL, Springer MS |title=The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) cluster within 285 kb on human chromosome 3p21. |journal=Genomics |volume=41 |issue= 2 |pages= 294–5 |year= 1997 |pmid= 9143512 |doi= 10.1006/geno.1997.4626
*cite journal | author=Fan P, Kyaw H, Su K, "et al." |title=Cloning and characterization of a novel human chemokine receptor. |journal=Biochem. Biophys. Res. Commun. |volume=243 |issue= 1 |pages= 264–8 |year= 1998 |pmid= 9473515 |doi= 10.1006/bbrc.1997.7981
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Galligan CL, Matsuyama W, Matsukawa A, "et al." |title=Up-regulated expression and activation of the orphan chemokine receptor, CCRL2, in rheumatoid arthritis. |journal=Arthritis Rheum. |volume=50 |issue= 6 |pages= 1806–14 |year= 2004 |pmid= 15188357 |doi= 10.1002/art.20275
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Muzny DM, Scherer SE, Kaul R, "et al." |title=The DNA sequence, annotation and analysis of human chromosome 3. |journal=Nature |volume=440 |issue= 7088 |pages= 1194–8 |year= 2006 |pmid= 16641997 |doi= 10.1038/nature04728

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