Omega-amidase

omega-amidase
Identifiers
EC number	3.5.1.3
CAS number	9025-19-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, an omega-amidase (EC 3.5.1.3) is an enzyme that catalyzes the chemical reaction

a monoamide of a dicarboxylic acid + H₂O $\rightleftharpoons$ a dicarboxylate + NH₃

Thus, the two substrates of this enzyme are monoamide of a dicarboxylic acid and H₂O, whereas its two products are dicarboxylate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is omega-amidodicarboxylate amidohydrolase. This enzyme is also called alpha-keto acid-omega-amidase. This enzyme participates in glutamate metabolism and alanine and aspartate metabolism.

References

• MEISTER A, LEVINTOW L, GREENFIELD RE, ABENDSCHEIN PA (1955). "Hydrolysis and transfer reactions catalyzed by omega-amidase preparations". J. Biol. Chem. 215 (1): 441–60. PMID 14392177. 
• Meister A, Radhakrishnan AN and Buckley SD (1957). "Enzymatic synthesis of L-pipecolic acid and L-proline". J. Biol. Chem. 229: 789–800. PMID 13502341. 

This hydrolase article is a stub. You can help Wikipedia by expanding it.v · Categories: EC 3.5.1 Enzymes of unknown structure Hydrolase stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем сделать НИР A Truce, and Other Stories Aliens (1902 novel) Look at other dictionaries: List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”