N-(long-chain-acyl)ethanolamine deacylase

N-(long-chain-acyl)ethanolamine deacylase
N-(long-chain-acyl)ethanolamine deacylase
Identifiers
EC number 3.5.1.60
CAS number 99283-61-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a N-(long-chain-acyl)ethanolamine deacylase (EC 3.5.1.60) is an enzyme that catalyzes the chemical reaction

N-(long-chain-acyl)ethanolamine + H2O \rightleftharpoons a long-chain carboxylate + ethanolamine

Thus, the two substrates of this enzyme are N-(long-chain-acyl)ethanolamine and H2O, whereas its two products are long-chain carboxylate and ethanolamine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-(long-chain-acyl)ethanolamine amidohydrolase. Other names in common use include N-acylethanolamine amidohydrolase, and acylethanolamine amidase.

References

  • Schmid PC, Zuzarte-Augustin ML, Schmid HH (1985). "Properties of rat liver N-acylethanolamine amidohydrolase". J. Biol. Chem. 260 (26): 14145–9. PMID 4055775. 
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