- Mandelamide amidase
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mandelamide amidase Identifiers EC number 3.5.1.86 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a mandelamide amidase (EC 3.5.1.86) is an enzyme that catalyzes the chemical reaction
- (R)-mandelamide + H2O (R)-mandelate + NH3
Thus, the two substrates of this enzyme are (R)-mandelamide and H2O, whereas its two products are (R)-mandelate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is mandelamide hydrolase. This enzyme is also called Pseudomonas mandelamide hydrolase.
References
- Yamamoto K, Oishi K, Fujimatsu I, Komatsu K (1991). "Production of R-(-)-mandelic acid from mandelonitrile by Alcaligenes faecalis ATCC 8750". Appl. Environ. Microbiol. 57 (10): 3028–32. PMC 183915. PMID 1660699. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=183915.
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