Formamidase

In enzymology, a formamidase (EC number|3.5.1.49) is an enzyme that catalyzes the chemical reaction

:formamide + H₂O $ightleftharpoons$ formate + NH₃

Thus, the two substrates of this enzyme are formamide and H₂O, whereas its two products are formate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is formamide amidohydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism and nitrogen metabolism.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2DYU, PDB link|2DYV, PDB link|2E2K, and PDB link|2E2L.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9013-59-6."

Gene Ontology (GO) codes