D-glutaminase

D-glutaminase
D-glutaminase
Identifiers
EC number 3.5.1.35
CAS number 37289-12-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a D-glutaminase (EC 3.5.1.35) is an enzyme that catalyzes the chemical reaction

D-glutamine + H2O \rightleftharpoons D-glutamate + NH3

Thus, the two substrates of this enzyme are D-glutamine and H2O, whereas its two products are D-glutamate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is D-glutamine amidohydrolase. This enzyme participates in d-glutamine and d-glutamate metabolism and nitrogen metabolism.

References

  • Domnas A and Catimo EC (1965). "The behavior of amidohydrolases and L-glutamate in synchronized populations of Blastocladiella emeronii". Phytochemistry 4 (2): 273–284. doi:10.1016/S0031-9422(00)86173-7.