N-methyl nucleosidase

N-methyl nucleosidase
Identifiers
EC number	3.2.2.25
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles

In enzymology, a N-methyl nucleosidase (EC 3.2.2.25) is an enzyme that catalyzes the chemical reaction

7-methylxanthosine + H₂O $\rightleftharpoons$ 7-methylxanthine + D-ribose

Thus, the two substrates of this enzyme are 7-methylxanthosine and H₂O, whereas its two products are 7-methylxanthine and D-ribose.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is 7-methylxanthosine ribohydrolase. Other names in common use include 7-methylxanthosine nucleosidase, N-MeNase, N-methyl nucleoside hydrolase, and methylpurine nucleosidase.

References

• Negishi O, Ozawa T and Imagawa H (1988). "N-Methyl nucleosidase from tea leaves". Agric. Biol. Chem. 52: 169–175. 

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