Phosphatidate phosphatase

Phosphatidate phosphatase

In enzymology, a phosphatidate phosphatase (EC number|3.1.3.4) is an enzyme that catalyzes the chemical reaction

:a 3-sn-phosphatidate + H2O ightleftharpoons a 1,2-diacyl-sn-glycerol + phosphate

Thus, the two substrates of this enzyme are 3-sn-phosphatidate and H2O, whereas its two products are 1,2-diacyl-sn-glycerol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 3-sn-phosphatidate phosphohydrolase. Other names in common use include phosphatic acid phosphatase, acid phosphatidyl phosphatase, and phosphatic acid phosphohydrolase. This enzyme participates in 4 metabolic pathways: glycerolipid metabolism, glycerophospholipid metabolism, ether lipid metabolism, and sphingolipid metabolism.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|9025-77-8."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • phosphatidate phosphatase — phos·pha·ti·date phos·pha·tase (fos″fə tiґdāt fosґfə tās) [EC 3.1.3.4] an enzyme of the hydrolase class that catalyzes the cleavage of a phosphate group from a phosphatidate to form a diglyceride; the reaction is a step… …   Medical dictionary

  • phosphatidate — A salt or ester of a phosphatidic acid. p. phosphatase an enzyme that catalyzes the hydrolysis of p. producing orthophosphate and 1,2 diacylglycerol; this enzyme participates in phospholipid and triacylglycerol metabo …   Medical dictionary

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français

  • Diacylglycerol kinase — catalytic domain Identifiers Symbol DAGK cat Pfam PF00781 Pfam clan …   Wikipedia

  • LPIN1 — Lipin 1, also known as LPIN1, is a human gene.cite web | title = Entrez Gene: LPIN1 lipin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=23175| accessdate = ] PBB Summary section title = summary text =… …   Wikipedia

  • CDS1 (gene) — CDP diacylglycerol synthase (phosphatidate cytidylyltransferase) 1, also known as CDS1, is a human gene.cite web | title = Entrez Gene: CDS1 CDP diacylglycerol synthase (phosphatidate cytidylyltransferase) 1| url =… …   Wikipedia

  • Cardiolipin — (alternate image) Cardiolip …   Wikipedia

  • phospholipase — An enzyme that catalyzes the hydrolysis of a phospholipid. SYN: lecithinase. p. A1 an enzyme that hydrolyzes a lecithin (1,2 diacylglycerophosphocholine) to a 2 acylglycerophosphocholine and a fatty acid anion. p. A2 an enzyme that catalyzes the… …   Medical dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”