Glycerophosphodiester phosphodiesterase
- Glycerophosphodiester phosphodiesterase
In enzymology, a glycerophosphodiester phosphodiesterase (EC number|3.1.4.46) is an enzyme that catalyzes the chemical reaction
:a glycerophosphodiester + H2O an alcohol + sn-glycerol 3-phosphate
Thus, the two substrates of this enzyme are glycerophosphodiester and H2O, whereas its two products are alcohol and sn-glycerol 3-phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is glycerophosphodiester glycerophosphohydrolase. Other names in common use include gene hpd protein, glycerophosphoryl diester phosphodiesterase, and IgD-binding protein D. This enzyme participates in glycerophospholipid metabolism.
tructural studies
As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1O1Z, PDB link|1T8Q, PDB link|1V8E, PDB link|1VD6, PDB link|1YDY, PDB link|2DXL, PDB link|2DXN, PDB link|2OOG, and PDB link|2P76.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|86280-59-3."
Gene Ontology (GO) codes
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