- Dolichylphosphate-mannose phosphodiesterase
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dolichylphosphate-mannose phosphodiesterase Identifiers EC number 3.1.4.49 CAS number 111839-07-7 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a dolichylphosphate-mannose phosphodiesterase (EC 3.1.4.49) is an enzyme that catalyzes the chemical reaction
- dolichyl beta-D-mannosyl phosphate + H2O dolichyl phosphate + D-mannose
Thus, the two substrates of this enzyme are dolichyl beta-D-mannosyl phosphate and H2O, whereas its two products are dolichyl phosphate and D-mannose.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase. This enzyme is also called mannosylphosphodolichol phosphodiesterase.
References
- Tomita Y, Motokawa Y (1987). "Characterization and partial purification of a novel mannosylphosphodolichol phosphodiesterase from chicken liver microsomes". Eur. J. Biochem. 170 (1–2): 363–8. doi:10.1111/j.1432-1033.1987.tb13708.x. PMID 2826159.
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