Citrate lyase deacetylase

[citrate-(pro-3S)-lyase] thiolesterase
Identifiers
EC number	3.1.2.16
CAS number	58319-93-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a citrate lyase deacetylase (EC 3.1.2.16) is an enzyme that catalyzes the chemical reaction

[citrate (pro-3S)-lyase](acetyl form) + H₂O $\rightleftharpoons$ [citrate (pro-3S)-lyase](thiol form) + acetate

Thus, the two substrates of this enzyme are [[[citrate (pro-3S)-lyase](acetyl form)]] and H₂O, whereas its two products are [[[citrate (pro-3S)-lyase](thiol form)]] and acetate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is [citrate-(pro-3S)-lyase](acetyl-form) hydrolase. This enzyme is also called [citrate-(pro-3S)-lyase] thiolesterase.

References

• Giffhorn F, Rode H, Kuhn A, Gottschalk G (1980). "Citrate lyase deacetylase of Rhodopseudomonas gelatinosa. Isolation of the enzyme and studies on the inhibition by L-glutamate". Eur. J. Biochem. 111 (2): 461–71. doi:10.1111/j.1432-1033.1980.tb04961.x. PMID 7460909. 

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