4-hydroxybenzoyl-CoA thioesterase

4-hydroxybenzoyl-CoA thioesterase

In enzymology, a 4-hydroxybenzoyl-CoA thioesterase (EC number|3.1.2.23) is an enzyme that catalyzes the chemical reaction

:4-hydroxybenzoyl-CoA + H2O ightleftharpoons 4-hydroxybenzoate + CoA

Thus, the two substrates of this enzyme are 4-hydroxybenzoyl-CoA and H2O, whereas its two products are 4-hydroxybenzoate and CoA.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is 4-hydroxybenzoyl-CoA hydrolase. This enzyme participates in 2,4-dichlorobenzoate degradation.

tructural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1HN1, PDB link|1LO7, PDB link|1LO8, PDB link|1LO9, PDB link|1Q4S, PDB link|1Q4T, and PDB link|1Q4U.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|141583-19-9."

Gene Ontology (GO) codes


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