Nonpolar-amino-acid-transporting ATPase

Nonpolar-amino-acid-transporting ATPase
nonpolar-amino acid-transporting ATPase
Identifiers
EC number 3.6.3.22
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a nonpolar-amino-acid-transporting ATPase (EC 3.6.3.22) is an enzyme that catalyzes the chemical reaction

ATP + H2O + nonpolar amino acidout \rightleftharpoons ADP + phosphate + nonpolar amino acidin

The 3 substrates of this enzyme are ATP, H2O, and nonpolar amino acid, whereas its 3 products are ADP, phosphate, and nonpolar amino acid.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (nonpolar-amino-acid-transporting).

References

  • Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. doi:10.1016/0923-2508(96)81050-3. PMID 7569321. 
  • Saier MH Jr (1998). Molecular Phylogeny as a Basis for the Classification of Transport Proteins from Bacteria, Archaea and Eukarya. "Advances in Microbial Physiology Volume 40". Adv. Microb. Physiol.. Advances in Microbial Physiology 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 9780120277407. PMID 9889977. 
  • Griffiths JK and Sansom CE. The Transporter Factsbook, Academic Press, San Diego, 1998. 


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