Tubulin-tyrosine ligase

Tubulin-tyrosine ligase

In enzymology, a tubulin-tyrosine ligase (EC number|6.3.2.25) is an enzyme that catalyzes the chemical reaction

:ATP + detyrosinated alpha-tubulin + L-tyrosine ightleftharpoons alpha-tubulin + ADP + phosphate

The 3 substrates of this enzyme are ATP, detyrosinated alpha-tubulin, and L-tyrosine, whereas its 3 products are alpha-tubulin, ADP, and phosphate.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is alpha-tubulin:L-tyrosine ligase (ADP-forming).

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|60321-03-1."

Gene Ontology (GO) codes


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