Biotin-(methylmalonyl-CoA-carboxytransferase) ligase

In enzymology, a biotin- [methylmalonyl-CoA-carboxytransferase] ligase (EC number|6.3.4.9) is an enzyme that catalyzes the chemical reaction

:ATP + biotin + apo- [methylmalonyl-CoA:pyruvate carboxytransferase] $ightleftharpoons$ AMP + diphosphate + [methylmalonyl-CoA:pyruvate carboxytransferase]

The 3 substrates of this enzyme are ATP, biotin, and ] , whereas its 3 products are AMP, diphosphate, and ] .

This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is biotin:apo [methylmalonyl-CoA:pyruvate carboxytransferase] ligase (AMP-forming). Other names in common use include biotin- [methylmalonyl-CoA-carboxyltransferase] synthetase, biotin-methylmalonyl coenzyme A carboxyltransferase synthetase, biotin-transcarboxylase synthetase, methylmalonyl coenzyme A holotranscarboxylase synthetase, biotin- [methylmalonyl-CoA-carboxyltransferase] ligase, biotin:apo [methylmalonyl-CoA:pyruvate carboxyltransferase] ligase, and (AMP-forming). This enzyme participates in biotin metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37318-66-4."

Gene Ontology (GO) codes