4-chlorobenzoate dehalogenase

4-chlorobenzoate dehalogenase

In enzymology, a 4-chlorobenzoate dehalogenase (EC number|3.8.1.6) is an enzyme that catalyzes the chemical reaction

:4-chlorobenzoate + H2O ightleftharpoons 4-hydroxybenzoate + chloride

Thus, the two substrates of this enzyme are 4-chlorobenzoate and H2O, whereas its two products are 4-hydroxybenzoate and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is 4-chlorobenzoate chlorohydrolase. This enzyme is also called halobenzoate dehalogenase.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1BVQ, PDB link|1JXZ, and PDB link|1NZY.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|94047-11-7."

Gene Ontology (GO) codes


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