Galactosylceramide sulfotransferase

In enzymology, a galactosylceramide sulfotransferase (EC number|2.8.2.11) is an enzyme that catalyzes the chemical reaction

:3'-phosphoadenylyl sulfate + a galactosylceramide $ightleftharpoons$ adenosine 3',5'-bisphosphate + a galactosylceramidesulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and galactosylceramide, whereas its two products are adenosine 3',5'-bisphosphate and galactosylceramidesulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase. Other names in common use include GSase, 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase, galactocerebroside sulfotransferase, galactolipid sulfotransferase, glycolipid sulfotransferase, and glycosphingolipid sulfotransferase. This enzyme participates in sphingolipid metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9081-06-5."

Gene Ontology (GO) codes