GAL3ST1

GAL3ST1

Galactose-3-O-sulfotransferase 1, also known as GAL3ST1, is a human gene.cite web | title = Entrez Gene: GAL3ST1 galactose-3-O-sulfotransferase 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9514| accessdate = ]

PBB_Summary
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summary_text = Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma.cite web | title = Entrez Gene: GAL3ST1 galactose-3-O-sulfotransferase 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9514| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Siegrist HP, Jutzi H, Steck AJ, "et al." |title=Age-dependent modulation of 3'-phosphoadenosine-5'-phosphosulfate-galactosylceramide sulfotransferase by lipids extracted from the microsomal membranes and artificial lipid mixtures. |journal=Biochim. Biophys. Acta |volume=489 |issue= 1 |pages= 58–63 |year= 1977 |pmid= 911873 |doi=
*cite journal | author=Stein C, Gieselmann V, Kreysing J, "et al." |title=Cloning and expression of human arylsulfatase A. |journal=J. Biol. Chem. |volume=264 |issue= 2 |pages= 1252–9 |year= 1989 |pmid= 2562955 |doi=
*cite journal | author=Fleischer B, Zambrano F |title=Localization of cerebroside-sulfotransferase activity in the Golgi apparatus of rat kidney. |journal=Biochem. Biophys. Res. Commun. |volume=52 |issue= 3 |pages= 951–8 |year= 1973 |pmid= 4710574 |doi=
*cite journal | author=Farrell DF, McKhann GM |title=Characterization of cerebroside sulfotransferase from rat brain. |journal=J. Biol. Chem. |volume=246 |issue= 15 |pages= 4694–702 |year= 1971 |pmid= 5562350 |doi=
*cite journal | author=Costantino-Ceccarini E, Waehneldt TV, Ginalski H, "et al." |title=Distribution of lipid synthesizing enzymes, 2',3'-cyclic nucleotide 3'-phosphodiesterase, and myelin proteins in rat forebrain subfractions during development. |journal=Neurochem. Res. |volume=7 |issue= 1 |pages= 1–12 |year= 1982 |pmid= 6280086 |doi=
*cite journal | author=Benjamins JA, Hadden T, Skoff RP |title=Cerebroside sulfotransferase in Golgi-enriched fractions from rat brain. |journal=J. Neurochem. |volume=38 |issue= 1 |pages= 233–41 |year= 1982 |pmid= 6955451 |doi=
*cite journal | author=Honke K, Yamane M, Ishii A, "et al." |title=Purification and characterization of 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase from human renal cancer cells. |journal=J. Biochem. |volume=119 |issue= 3 |pages= 421–7 |year= 1996 |pmid= 8830034 |doi=
*cite journal | author=Honke K, Tsuda M, Hirahara Y, "et al." |title=Molecular cloning and expression of cDNA encoding human 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase. |journal=J. Biol. Chem. |volume=272 |issue= 8 |pages= 4864–8 |year= 1997 |pmid= 9030544 |doi=
*cite journal | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=
*cite journal | author=Tsuda M, Egashira M, Niikawa N, "et al." |title=Cancer-associated alternative usage of multiple promoters of human GalCer sulfotransferase gene. |journal=Eur. J. Biochem. |volume=267 |issue= 9 |pages= 2672–9 |year= 2000 |pmid= 10785389 |doi=
*cite journal | author=Eckhardt M, Fewou SN, Ackermann I, Gieselmann V |title=N-glycosylation is required for full enzymic activity of the murine galactosylceramide sulphotransferase. |journal=Biochem. J. |volume=368 |issue= Pt 1 |pages= 317–24 |year= 2002 |pmid= 12175333 |doi= 10.1042/BJ20020946
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Collins JE, Wright CL, Edwards CA, "et al." |title=A genome annotation-driven approach to cloning the human ORFeome. |journal=Genome Biol. |volume=5 |issue= 10 |pages= R84 |year= 2005 |pmid= 15461802 |doi= 10.1186/gb-2004-5-10-r84
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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