Glycine formimidoyltransferase

In enzymology, a glycine formimidoyltransferase (EC number|2.1.2.4) is an enzyme that catalyzes the chemical reaction

:5-formimidoyltetrahydrofolate + glycine $ightleftharpoons$ tetrahydrofolate + N-formimidoylglycine

Thus, the two substrates of this enzyme are 5-formimidoyltetrahydrofolate and glycine, whereas its two products are tetrahydrofolate and N-formimidoylglycine.

This enzyme belongs to the family of transferases that transfer one-carbon groups, specifically the hydroxymethyl-, formyl- and related transferases. The systematic name of this enzyme class is 5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase. Other names in common use include formiminoglycine formiminotransferase, FIG formiminotransferase, and glycine formiminotransferase. This enzyme participates in purine metabolism and one carbon pool by folate.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9029-84-9."

Gene Ontology (GO) codes