- Dihydroxyphenylalanine ammonia-lyase
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dihydroxyphenylalanine ammonia-lyase Identifiers EC number 4.3.1.11 CAS number 37290-92-9 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a dihydroxyphenylalanine ammonia-lyase (EC 4.3.1.11) is an enzyme that catalyzes the chemical reaction
- 3,4-dihydroxy-L-phenylalanine
trans-caffeate + NH3
Hence, this enzyme has one substrate, 3,4-dihydroxy-L-phenylalanine, and two products, trans-caffeate and NH3.
This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is 3,4-dihydroxy-L-phenylalanine ammonia-lyase (trans-caffeate-forming). Other names in common use include beta-(3,4-dihydroxyphenyl)-L-alanine (DOPA) ammonia-lyase, and 3,4-dihydroxy-L-phenylalanine ammonia-lyase. This enzyme participates in tyrosine metabolism.
References
- MacLeod NJ and Pridham JB (1963). "Deamination of beta-(3,4-dihydroxyphenyl)-L-alanine by plants". Biochem. J. 88 (1): 45. PMC 1203845. PMID 16749027. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1203845.
This lyase article is a stub. You can help Wikipedia by expanding it. - 3,4-dihydroxy-L-phenylalanine