Mannose isomerase

Mannose isomerase
mannose isomerase
Identifiers
EC number 5.3.1.7
CAS number 9031-25-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a mannose isomerase (EC 5.3.1.7) is an enzyme that catalyzes the chemical reaction

D-mannose \rightleftharpoons D-fructose

Hence, this enzyme has one substrate, D-mannose, and one product, D-fructose.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-mannose aldose-ketose-isomerase. Other names in common use include D-mannose isomerase, and D-mannose ketol-isomerase. This enzyme participates in fructose and mannose metabolism.

References

  • Palleroni NJ and Doudoroff M (1956). "Mannose isomerase of Pseudomonas saccharophila". J. Biol. Chem. 218: 535–548. PMID 13278359.