Delta1-piperideine-2-carboxylate reductase

Delta1-piperideine-2-carboxylate reductase
delta1-piperideine-2-carboxylate reductase
Identifiers
EC number 1.5.1.21
CAS number 52037-88-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a Delta1-piperideine-2-carboxylate reductase (EC 1.5.1.21) is an enzyme that catalyzes the chemical reaction

L-pipecolate + NADP+ \rightleftharpoons Delta1-piperideine-2-carboxylate + NADPH + H+

Thus, the two substrates of this enzyme are L-pipecolate and NADP+, whereas its 3 products are Delta1-piperideine-2-carboxylate, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-pipecolate:NADP+ 2-oxidoreductase. Other names in common use include 1,2-didehydropipecolate reductase, P2C reductase, and 1,2-didehydropipecolic reductase. This enzyme participates in lysine degradation.

References