- Delta1-piperideine-2-carboxylate reductase
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delta1-piperideine-2-carboxylate reductase Identifiers EC number 1.5.1.21 CAS number 52037-88-4 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a Delta1-piperideine-2-carboxylate reductase (EC 1.5.1.21) is an enzyme that catalyzes the chemical reaction
- L-pipecolate + NADP+ Delta1-piperideine-2-carboxylate + NADPH + H+
Thus, the two substrates of this enzyme are L-pipecolate and NADP+, whereas its 3 products are Delta1-piperideine-2-carboxylate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-pipecolate:NADP+ 2-oxidoreductase. Other names in common use include 1,2-didehydropipecolate reductase, P2C reductase, and 1,2-didehydropipecolic reductase. This enzyme participates in lysine degradation.
References
- Payton CW, Chang YF (1982). "delta1-piperideine-2-carboxylate reductase of Pseudomonas putida". J. Bacteriol. 149 (3): 864–71. PMC 216472. PMID 6801013. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=216472.
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