Cyclohexylamine oxidase

Cyclohexylamine oxidase
cyclohexylamine oxidase
Identifiers
EC number 1.4.3.12
CAS number 63116-97-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a cyclohexylamine oxidase (EC 1.4.3.12) is an enzyme that catalyzes the chemical reaction

cyclohexylamine + O2 + H2O \rightleftharpoons cyclohexanone + NH3 + H2O2

The 3 substrates of this enzyme are cyclohexylamine, O2, and H2O, whereas its 3 products are cyclohexanone, NH3, and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is cyclohexylamine:oxygen oxidoreductase (deaminating). This enzyme participates in caprolactam degradation. It employs one cofactor, FAD.

References

  • Tokieda T, Niimura T, Takamura F, Yamaha T (Tokyo). "Purification and some properties of cyclohexylamine oxidase from a Pseudomonas sp". J. Biochem. (4): 851–8. PMID 18451.