CoB-CoM heterodisulfide reductase
- CoB-CoM heterodisulfide reductase
In enzymology, a CoB---CoM heterodisulfide reductase (EC number|1.8.98.1) is an enzyme that catalyzes the chemical reaction
:coenzyme B + coenzyme M + methanophenazine N-{7- [(2-sulfoethyl)dithio] heptanoyl}-O3-phospho-L-threonine + dihydromethanophenazine
The 3 substrates of this enzyme are coenzyme B, coenzyme M, and methanophenazine, whereas its two products are [N-{7- [(2-sulfoethyl)dithio] heptanoyl}-O3-phospho-L-threonine] and dihydromethanophenazine.
This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with other, known, acceptors. The systematic name of this enzyme class is coenzyme B:coenzyme M:methanophenazine oxidoreductase. Other names in common use include heterodisulfide reductase, and soluble heterodisulfide reductase. This enzyme participates in folate biosynthesis.
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External links
Gene Ontology (GO) codes
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