Bis-gamma-glutamylcystine reductase

In enzymology, a bis-gamma-glutamylcystine reductase (EC number|1.8.1.13) is an enzyme that catalyzes the chemical reaction

:2 gamma-glutamylcysteine + NADP⁺ $ightleftharpoons$ bis-gamma-glutamylcystine + NADPH + H⁺

Thus, the two substrates of this enzyme are gamma-glutamylcysteine and NADP⁺, whereas its 3 products are bis-gamma-glutamylcystine, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is gamma-glutamylcysteine:NADP+ oxidoreductase. This enzyme is also called NADPH2:bis-gamma-glutamylcysteine oxidoreductase. This enzyme participates in glutathione metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|117056-54-9."

Gene Ontology (GO) codes