NCF1

Neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1), also known as NCF1, is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.cite web | title = Entrez Gene: NCF1 neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=653361| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Dorseuil O, Gacon G |title= [Signal transduction by Rac small G proteins in phagocytes] |journal=C. R. Seances Soc. Biol. Fil. |volume=191 |issue= 2 |pages= 237–46 |year= 1997 |pmid= 9255350 |doi=
*cite journal | author=Casimir CM, Bu-Ghanim HN, Rodaway AR, "et al." |title=Autosomal recessive chronic granulomatous disease caused by deletion at a dinucleotide repeat. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 7 |pages= 2753–7 |year= 1991 |pmid= 2011585 |doi=
*cite journal | author=Rodaway AR, Teahan CG, Casimir CM, "et al." |title=Characterization of the 47-kilodalton autosomal chronic granulomatous disease protein: tissue-specific expression and transcriptional control by retinoic acid. |journal=Mol. Cell. Biol. |volume=10 |issue= 10 |pages= 5388–96 |year= 1990 |pmid= 2398896 |doi=
*cite journal | author=Lomax KJ, Leto TL, Nunoi H, "et al." |title=Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease. |journal=Science |volume=245 |issue= 4916 |pages= 409–12 |year= 1989 |pmid= 2547247 |doi=
*cite journal | author=Volpp BD, Nauseef WM, Donelson JE, "et al." |title=Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 18 |pages= 7195–9 |year= 1989 |pmid= 2550933 |doi=
*cite journal | author=Volpp BD, Nauseef WM, Clark RA |title=Two cytosolic neutrophil oxidase components absent in autosomal chronic granulomatous disease. |journal=Science |volume=242 |issue= 4883 |pages= 1295–7 |year= 1989 |pmid= 2848318 |doi=
*cite journal | author=Miki Y, Swensen J, Shattuck-Eidens D, "et al." |title=A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. |journal=Science |volume=266 |issue= 5182 |pages= 66–71 |year= 1994 |pmid= 7545954 |doi=
*cite journal | author=Leto TL, Adams AG, de Mendez I |title=Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 22 |pages= 10650–4 |year= 1994 |pmid= 7938008 |doi=
*cite journal | author=el Benna J, Faust LP, Babior BM |title=The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases. |journal=J. Biol. Chem. |volume=269 |issue= 38 |pages= 23431–6 |year= 1994 |pmid= 8089108 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Finan PM, Hall A, Kellie S |title=Sam68 from an immortalised B-cell line associates with a subset of SH3 domains. |journal=FEBS Lett. |volume=389 |issue= 2 |pages= 141–4 |year= 1996 |pmid= 8766817 |doi=
*cite journal | author=Sathyamoorthy M, de Mendez I, Adams AG, Leto TL |title=p40(phox) down-regulates NADPH oxidase activity through interactions with its SH3 domain. |journal=J. Biol. Chem. |volume=272 |issue= 14 |pages= 9141–6 |year= 1997 |pmid= 9083043 |doi=
*cite journal | author=Görlach A, Lee PL, Roesler J, "et al." |title=A p47-phox pseudogene carries the most common mutation causing p47-phox- deficient chronic granulomatous disease. |journal=J. Clin. Invest. |volume=100 |issue= 8 |pages= 1907–18 |year= 1997 |pmid= 9329953 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Izuhara K, Arinobu Y, Sumimoto H, "et al." |title=Association of the interleukin-4 receptor alpha chain with p47phox, an activator of the phagocyte NADPH oxidase in B cells. |journal=Mol. Immunol. |volume=36 |issue= 1 |pages= 45–52 |year= 1999 |pmid= 10369419 |doi=
*cite journal | author=Nakamura F, Huang L, Pestonjamasp K, "et al." |title=Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides. |journal=Mol. Biol. Cell |volume=10 |issue= 8 |pages= 2669–85 |year= 1999 |pmid= 10436021 |doi=
*cite journal | author=Rinckel LA, Faris SL, Hitt ND, Kleinberg ME |title=Rac1 disrupts p67phox/p40phox binding: a novel role for Rac in NADPH oxidase activation. |journal=Biochem. Biophys. Res. Commun. |volume=263 |issue= 1 |pages= 118–22 |year= 1999 |pmid= 10486263 |doi= 10.1006/bbrc.1999.1334
*cite journal | author=Chanock SJ, Roesler J, Zhan S, "et al." |title=Genomic structure of the human p47-phox (NCF1) gene. |journal=Blood Cells Mol. Dis. |volume=26 |issue= 1 |pages= 37–46 |year= 2000 |pmid= 10772875 |doi= 10.1006/bcmd.2000.0274
*cite journal | author=Onofri F, Giovedi S, Kao HT, "et al." |title=Specificity of the binding of synapsin I to Src homology 3 domains. |journal=J. Biol. Chem. |volume=275 |issue= 38 |pages= 29857–67 |year= 2000 |pmid= 10899172 |doi= 10.1074/jbc.M006018200

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