Adenylyl-sulfate reductase (thioredoxin)

In enzymology, an adenylyl-sulfate reductase (thioredoxin) (EC number|1.8.4.10) is an enzyme that catalyzes the chemical reaction

:AMP + sulfite + thioredoxin disulfide $ightleftharpoons$ 5'-adenylyl sulfate + thioredoxin

The 3 substrates of this enzyme are AMP, sulfite, and thioredoxin disulfide, whereas its two products are 5'-adenylyl sulfate and thioredoxin.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming). This enzyme is also called thioredoxin-dependent 5'-adenylylsulfate reductase.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2GOY.

References

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External links

Gene Ontology (GO) codes