MNAT1

Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis), also known as MNAT1, is a human gene.

PBB_Summary
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summary_text = Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK). CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH; MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex. [supplied by OMIM] cite web | title = Entrez Gene: MNAT1 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4331| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Jeang KT |title=Tat, Tat-associated kinase, and transcription. |journal=J. Biomed. Sci. |volume=5 |issue= 1 |pages= 24–7 |year= 1998 |pmid= 9570510 |doi=
*cite journal | author=Yankulov K, Bentley D |title=Transcriptional control: Tat cofactors and transcriptional elongation. |journal=Curr. Biol. |volume=8 |issue= 13 |pages= R447–9 |year= 1998 |pmid= 9651670 |doi=
*cite journal | author=Le Goff P, Montano MM, Schodin DJ, Katzenellenbogen BS |title=Phosphorylation of the human estrogen receptor. Identification of hormone-regulated sites and examination of their influence on transcriptional activity. |journal=J. Biol. Chem. |volume=269 |issue= 6 |pages= 4458–66 |year= 1994 |pmid= 8308015 |doi=
*cite journal | author=Yee A, Nichols MA, Wu L, "et al." |title=Molecular cloning of CDK7-associated human MAT1, a cyclin-dependent kinase-activating kinase (CAK) assembly factor. |journal=Cancer Res. |volume=55 |issue= 24 |pages= 6058–62 |year= 1996 |pmid= 8521393 |doi=
*cite journal | author=Tassan JP, Jaquenoud M, Fry AM, "et al." |title=In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein. |journal=EMBO J. |volume=14 |issue= 22 |pages= 5608–17 |year= 1996 |pmid= 8521818 |doi=
*cite journal | author=Blau J, Xiao H, McCracken S, "et al." |title=Three functional classes of transcriptional activation domain. |journal=Mol. Cell. Biol. |volume=16 |issue= 5 |pages= 2044–55 |year= 1996 |pmid= 8628270 |doi=
*cite journal | author=Reardon JT, Ge H, Gibbs E, "et al." |title=Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 13 |pages= 6482–7 |year= 1996 |pmid= 8692841 |doi=
*cite journal | author=Drapkin R, Le Roy G, Cho H, "et al." |title=Human cyclin-dependent kinase-activating kinase exists in three distinct complexes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 13 |pages= 6488–93 |year= 1996 |pmid= 8692842 |doi=
*cite journal | author=Zhou Q, Sharp PA |title=Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat. |journal=Science |volume=274 |issue= 5287 |pages= 605–10 |year= 1996 |pmid= 8849451 |doi=
*cite journal | author=Parada CA, Roeder RG |title=Enhanced processivity of RNA polymerase II triggered by Tat-induced phosphorylation of its carboxy-terminal domain. |journal=Nature |volume=384 |issue= 6607 |pages= 375–8 |year= 1996 |pmid= 8934526 |doi= 10.1038/384375a0
*cite journal | author=García-Martínez LF, Ivanov D, Gaynor RB |title=Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes. |journal=J. Biol. Chem. |volume=272 |issue= 11 |pages= 6951–8 |year= 1997 |pmid= 9054383 |doi=
*cite journal | author=Marinoni JC, Roy R, Vermeulen W, "et al." |title=Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH. |journal=EMBO J. |volume=16 |issue= 5 |pages= 1093–102 |year= 1997 |pmid= 9118947 |doi= 10.1093/emboj/16.5.1093
*cite journal | author=Cujec TP, Cho H, Maldonado E, "et al." |title=The human immunodeficiency virus transactivator Tat interacts with the RNA polymerase II holoenzyme. |journal=Mol. Cell. Biol. |volume=17 |issue= 4 |pages= 1817–23 |year= 1997 |pmid= 9121429 |doi=
*cite journal | author=Rossignol M, Kolb-Cheynel I, Egly JM |title=Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH. |journal=EMBO J. |volume=16 |issue= 7 |pages= 1628–37 |year= 1997 |pmid= 9130708 |doi= 10.1093/emboj/16.7.1628
*cite journal | author=García-Martínez LF, Mavankal G, Neveu JM, "et al." |title=Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription. |journal=EMBO J. |volume=16 |issue= 10 |pages= 2836–50 |year= 1997 |pmid= 9184228 |doi= 10.1093/emboj/16.10.2836
*cite journal | author=Nekhai S, Shukla RR, Kumar A |title=A human primary T-lymphocyte-derived human immunodeficiency virus type 1 Tat-associated kinase phosphorylates the C-terminal domain of RNA polymerase II and induces CAK activity. |journal=J. Virol. |volume=71 |issue= 10 |pages= 7436–41 |year= 1997 |pmid= 9311822 |doi=
*cite journal | author=Cujec TP, Okamoto H, Fujinaga K, "et al." |title=The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II. |journal=Genes Dev. |volume=11 |issue= 20 |pages= 2645–57 |year= 1997 |pmid= 9334327 |doi=
*cite journal | author=Inamoto S, Segil N, Pan ZQ, "et al." |title=The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors. |journal=J. Biol. Chem. |volume=272 |issue= 47 |pages= 29852–8 |year= 1997 |pmid= 9368058 |doi=
*cite journal | author=Ko LJ, Shieh SY, Chen X, "et al." |title=p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner. |journal=Mol. Cell. Biol. |volume=17 |issue= 12 |pages= 7220–9 |year= 1997 |pmid= 9372954 |doi=
*cite journal | author=Eki T, Okumura K, Abe M, "et al." |title=Mapping of the human genes encoding cyclin H (CCNH) and the CDK-activating kinase (CAK) assembly factor MAT1 (MNAT1) to chromosome bands 5q13.3-q14 and 14q23, respectively. |journal=Genomics |volume=47 |issue= 1 |pages= 115–20 |year= 1998 |pmid= 9465303 |doi= 10.1006/geno.1997.5053

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