L-ascorbate oxidase

In enzymology, a L-ascorbate oxidase (EC number|1.10.3.3) is an enzyme that catalyzes the chemical reaction

:2 L-ascorbate + O₂ $ightleftharpoons$ 2 dehydroascorbate + 2 H₂O

Thus, the two substrates of this enzyme are L-ascorbate and O₂, whereas its two products are dehydroascorbate and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with oxygen as acceptor. The systematic name of this enzyme class is L-ascorbate:oxygen oxidoreductase. Other names in common use include ascorbase, ascorbic acid oxidase, ascorbate oxidase, ascorbic oxidase, ascorbate dehydrogenase, L-ascorbic acid oxidase, AAO, L-ascorbate:O2 oxidoreductase, and AA oxidase. This enzyme participates in ascorbate metabolism. It employs one cofactor, copper.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1AOZ, PDB link|1ASO, PDB link|1ASP, and PDB link|1ASQ.

References

* Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 8, Academic Press, New York, 1963, p. 297-311.

External links

::"The CAS registry number for this enzyme class is CAS registry|9029-44-1."

Gene Ontology (GO) codes