Lactaldehyde dehydrogenase
- Lactaldehyde dehydrogenase
In enzymology, a lactaldehyde dehydrogenase (EC number|1.2.1.22) is an enzyme that catalyzes the chemical reaction
:(S)-lactaldehyde + NAD+ + H2O (S)-lactate + NADH + 2 H+
The 3 substrates of this enzyme are (S)-lactaldehyde, NAD+, and H2O, whereas its 3 products are (S)-lactate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-lactaldehyde:NAD+ oxidoreductase. Other names in common use include L-lactaldehyde:NAD+ oxidoreductase, and nicotinamide adenine dinucleotide (NAD+)-linked dehydrogenase. This enzyme participates in pyruvate metabolism.
tructural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2HG2, PDB link|2ILU, PDB link|2IMP, and PDB link|2OPX.
References
*
*
External links
::"The CAS registry number for this enzyme class is CAS registry|37250-90-1."
Gene Ontology (GO) codes
Wikimedia Foundation.
2010.
Look at other dictionaries:
Lactaldehyde reductase (NADPH) — In enzymology, a lactaldehyde reductase (NADPH) (EC number|1.1.1.55) is an enzyme that catalyzes the chemical reaction:propane 1,2 diol + NADP+ ightleftharpoons L lactaldehyde + NADPH + H+Thus, the two substrates of this enzyme are 1,2… … Wikipedia
Lactaldehyde — Chembox new ImageFile=lactaldehyde.png ImageSize=120px IUPACName=2 Hydroxypropanal OtherNames=Hydroxypropionaldehyde Section1= Chembox Identifiers CASNo=3913 65 3 CASOther= (R):CAS|3946 09 6 (S):CAS|3913 64 2 PubChem=855 ChemSpiderID = 832 SMILES … Wikipedia
List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH … Wikipedia
Methylglyoxal reductase (NADH-dependent) — Identifiers EC number 1.1.1.78 CAS number 37250 16 1 … Wikipedia
Methylglyoxal reductase (NADPH-dependent) — Identifiers EC number 1.1.1.283 Databases IntEnz Int … Wikipedia
Methylglyoxal pathway — The methylglyoxal pathway is an offshoot of glycolysis found in some prokaryotes, which converts glucose into methylglyoxal and then into pyruvate. However unlike glycolysis the methylglyoxal pathway does not produce adenosine triphosphate, ATP.… … Wikipedia