Lactaldehyde dehydrogenase

Lactaldehyde dehydrogenase

In enzymology, a lactaldehyde dehydrogenase (EC number|1.2.1.22) is an enzyme that catalyzes the chemical reaction

:(S)-lactaldehyde + NAD+ + H2O ightleftharpoons (S)-lactate + NADH + 2 H+

The 3 substrates of this enzyme are (S)-lactaldehyde, NAD+, and H2O, whereas its 3 products are (S)-lactate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-lactaldehyde:NAD+ oxidoreductase. Other names in common use include L-lactaldehyde:NAD+ oxidoreductase, and nicotinamide adenine dinucleotide (NAD+)-linked dehydrogenase. This enzyme participates in pyruvate metabolism.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2HG2, PDB link|2ILU, PDB link|2IMP, and PDB link|2OPX.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37250-90-1."

Gene Ontology (GO) codes


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