- APOA2
Apolipoprotein A-II, also known as APOA2, is a human
gene .PBB_Summary
section_title =
summary_text = This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.cite web | title = Entrez Gene: APOA2 apolipoprotein A-II| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=336| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Blanco-Vaca F, Escolà-Gil JC, Martín-Campos JM, Julve J |title=Role of apoA-II in lipid metabolism and atherosclerosis: advances in the study of an enigmatic protein. |journal=J. Lipid Res. |volume=42 |issue= 11 |pages= 1727–39 |year= 2002 |pmid= 11714842 |doi=
*cite journal | author=Kalopissis AD, Pastier D, Chambaz J |title=Apolipoprotein A-II: beyond genetic associations with lipid disorders and insulin resistance. |journal=Curr. Opin. Lipidol. |volume=14 |issue= 2 |pages= 165–72 |year= 2003 |pmid= 12642785 |doi= 10.1097/01.mol.0000064047.08840.50
*cite journal | author=Vollmer E, Brust J, Roessner A, "et al." |title=Distribution patterns of apolipoproteins A1, A2, and B in the wall of atherosclerotic vessels. |journal=Virchows Archiv. A, Pathological anatomy and histopathology |volume=419 |issue= 2 |pages= 79–88 |year= 1991 |pmid= 1908160 |doi=
*cite journal | author=Deeb SS, Takata K, Peng RL, "et al." |title=A splice-junction mutation responsible for familial apolipoprotein A-II deficiency. |journal=Am. J. Hum. Genet. |volume=46 |issue= 4 |pages= 822–7 |year= 1990 |pmid= 2107739 |doi=
*cite journal | author=Gordon JI, Sims HF, Edelstein C, "et al." |title=Extracellular processing of proapolipoprotein A-II in Hep G2 cell cultures is mediated by a 54-kDa protease immunologically related to cathepsin B. |journal=J. Biol. Chem. |volume=260 |issue= 27 |pages= 14824–31 |year= 1985 |pmid= 2414299 |doi=
*cite journal | author=Tsao YK, Wei CF, Robberson DL, "et al." |title=Isolation and characterization of the human apolipoprotein A-II gene. Electron microscopic analysis of RNA:DNA hybrids, nucleotide sequence, identification of a polymorphic MspI site, and general structural organization of apolipoprotein genes. |journal=J. Biol. Chem. |volume=260 |issue= 28 |pages= 15222–31 |year= 1986 |pmid= 2415515 |doi=
*cite journal | author=Lackner KJ, Law SW, Brewer HB |title=The human apolipoprotein A-II gene: complete nucleic acid sequence and genomic organization. |journal=Nucleic Acids Res. |volume=13 |issue= 12 |pages= 4597–608 |year= 1985 |pmid= 2989800 |doi=
*cite journal | author=Knott TJ, Wallis SC, Robertson ME, "et al." |title=The human apolipoprotein AII gene: structural organization and sites of expression. |journal=Nucleic Acids Res. |volume=13 |issue= 17 |pages= 6387–98 |year= 1985 |pmid= 2995928 |doi=
*cite journal | author=Chan L, Moore MN, Tsao YK |title=Molecular cloning and sequence analysis of human apolipoprotein A-II cDNA. |journal=Meth. Enzymol. |volume=128 |issue= |pages= 745–52 |year= 1986 |pmid= 3088392 |doi=
*cite journal | author=Middleton-Price HR, van den Berghe JA, Scott J, "et al." |title=Regional chromosomal localisation of APOA2 to 1q21-1q23. |journal=Hum. Genet. |volume=79 |issue= 3 |pages= 283–5 |year= 1988 |pmid= 3136074 |doi=
*cite journal | author=Shelley CS, Sharpe CR, Baralle FE, Shoulders CC |title=Comparison of the human apolipoprotein genes. Apo AII presents a unique functional intron-exon junction. |journal=J. Mol. Biol. |volume=186 |issue= 1 |pages= 43–51 |year= 1986 |pmid= 3935800 |doi=
*cite journal | author=Brewer HB, Lux SE, Ronan R, John KM |title=Amino acid sequence of human apoLp-Gln-II (apoA-II), an apolipoprotein isolated from the high-density lipoprotein complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=69 |issue= 5 |pages= 1304–8 |year= 1972 |pmid= 4338591 |doi=
*cite journal | author=Lux SE, John KM, Ronan R, Brewer HB |title=Isolation and characterization of the tryptic and cyanogen bromide peptides of apoLp-Gln-II (apoA-II), plasma high density apolipoprotein. |journal=J. Biol. Chem. |volume=247 |issue= 23 |pages= 7519–27 |year= 1973 |pmid= 4344225 |doi=
*cite journal | author=Moore MN, Kao FT, Tsao YK, Chan L |title=Human apolipoprotein A-II: nucleotide sequence of a cloned cDNA, and localization of its structural gene on human chromosome 1. |journal=Biochem. Biophys. Res. Commun. |volume=123 |issue= 1 |pages= 1–7 |year= 1984 |pmid= 6089788 |doi=
*cite journal | author=Lackner KJ, Law SW, Brewer HB |title=Human apolipoprotein A-II: complete nucleic acid sequence of preproapo A-II. |journal=FEBS Lett. |volume=175 |issue= 1 |pages= 159–64 |year= 1984 |pmid= 6090207 |doi=
*cite journal | author=Gordon JI, Budelier KA, Sims HF, "et al." |title=Biosynthesis of human preproapolipoprotein A-II. |journal=J. Biol. Chem. |volume=258 |issue= 22 |pages= 14054–9 |year= 1984 |pmid= 6315718 |doi=
*cite journal | author=Sharpe CR, Sidoli A, Shelley CS, "et al." |title=Human apolipoproteins AI, AII, CII and CIII. cDNA sequences and mRNA abundance. |journal=Nucleic Acids Res. |volume=12 |issue= 9 |pages= 3917–32 |year= 1984 |pmid= 6328445 |doi=
*cite journal | author=Stoffel W, Krüger E, Deutzmann R |title=Cell-free translation of human liver apolipoprotein AI and AII mRNA. Processing of primary translation products. |journal=Hoppe-Seyler's Z. Physiol. Chem. |volume=364 |issue= 3 |pages= 227–37 |year= 1983 |pmid= 6407957 |doi=
*cite journal | author=Knott TJ, Priestley LM, Urdea M, Scott J |title=Isolation and characterisation of a cDNA encoding the precursor for human apolipoprotein AII. |journal=Biochem. Biophys. Res. Commun. |volume=120 |issue= 3 |pages= 734–40 |year= 1984 |pmid= 6428397 |doi=
*cite journal | author=Lackner KJ, Law SW, Brewer HB, "et al." |title=The human apolipoprotein A-II gene is located on chromosome 1. |journal=Biochem. Biophys. Res. Commun. |volume=122 |issue= 3 |pages= 877–83 |year= 1984 |pmid= 6433912 |doi=PBB_Controls
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