- 2,5-dioxovalerate dehydrogenase
In
enzymology , a 2,5-dioxovalerate dehydrogenase (EC number|1.2.1.26) is anenzyme that catalyzes thechemical reaction :2,5-dioxopentanoate + NADP+ + H2O 2-oxoglutarate + NADPH + 2 H+
The 3 substrates of this enzyme are
2,5-dioxopentanoate , NADP+, and H2O, whereas its 3 products are2-oxoglutarate , NADPH, and H+.This enzyme belongs to the family of
oxidoreductase s, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,5-dioxopentanoate:NADP+ 5-oxidoreductase. Other names in common use include 2-oxoglutarate semialdehyde dehydrogenase, and alpha-ketoglutaric semialdehyde dehydrogenase. This enzyme participates inascorbate and aldarate metabolism .References
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External links
::"The
CAS registry number for this enzyme class is CAS registry|37250-92-3."Gene Ontology (GO) codes
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