HIST3H3

Histone cluster 3, H3, also known as HIST3H3, is a human gene.

PBB_Summary
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summary_text = Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [cite web | title = Entrez Gene: HIST3H3 histone cluster 3, H3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8290| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Govin J, Caron C, Rousseaux S, Khochbin S |title=Testis-specific histone H3 expression in somatic cells. |journal=Trends Biochem. Sci. |volume=30 |issue= 7 |pages= 357–9 |year= 2005 |pmid= 15922600 |doi= 10.1016/j.tibs.2005.05.001
*cite journal | author=Bernués J, Espel E, Querol E |title=Identification of the core-histone-binding domains of HMG1 and HMG2. |journal=Biochim. Biophys. Acta |volume=866 |issue= 4 |pages= 242–51 |year= 1986 |pmid= 3697355 |doi=
*cite journal | author=Ishimi Y, Ichinose S, Omori A, "et al." |title=Binding of human minichromosome maintenance proteins with histone H3. |journal=J. Biol. Chem. |volume=271 |issue= 39 |pages= 24115–22 |year= 1996 |pmid= 8798650 |doi=
*cite journal | author=Albig W, Ebentheuer J, Klobeck G, "et al." |title=A solitary human H3 histone gene on chromosome 1. |journal=Hum. Genet. |volume=97 |issue= 4 |pages= 486–91 |year= 1996 |pmid= 8834248 |doi=
*cite journal | author=Mizzen CA, Yang XJ, Kokubo T, "et al." |title=The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. |journal=Cell |volume=87 |issue= 7 |pages= 1261–70 |year= 1997 |pmid= 8980232 |doi=
*cite journal | author=Witt O, Albig W, Doenecke D |title=Testis-specific expression of a novel human H3 histone gene. |journal=Exp. Cell Res. |volume=229 |issue= 2 |pages= 301–6 |year= 1997 |pmid= 8986613 |doi= 10.1006/excr.1996.0375
*cite journal | author=Rodriguez P, Munroe D, Prawitt D, "et al." |title=Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone. |journal=Genomics |volume=44 |issue= 3 |pages= 253–65 |year= 1997 |pmid= 9325046 |doi= 10.1006/geno.1997.4868
*cite journal | author=Albig W, Doenecke D |title=The human histone gene cluster at the D6S105 locus. |journal=Hum. Genet. |volume=101 |issue= 3 |pages= 284–94 |year= 1998 |pmid= 9439656 |doi=
*cite journal | author=El Kharroubi A, Piras G, Zensen R, Martin MA |title=Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. |journal=Mol. Cell. Biol. |volume=18 |issue= 5 |pages= 2535–44 |year= 1998 |pmid= 9566873 |doi=
*cite journal | author=Zhang Y, Sun ZW, Iratni R, "et al." |title=SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. |journal=Mol. Cell |volume=1 |issue= 7 |pages= 1021–31 |year= 1998 |pmid= 9651585 |doi=
*cite journal | author=Lorain S, Quivy JP, Monier-Gavelle F, "et al." |title=Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA. |journal=Mol. Cell. Biol. |volume=18 |issue= 9 |pages= 5546–56 |year= 1998 |pmid= 9710638 |doi=
*cite journal | author=Becker W, Weber Y, Wetzel K, "et al." |title=Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. |journal=J. Biol. Chem. |volume=273 |issue= 40 |pages= 25893–902 |year= 1998 |pmid= 9748265 |doi=
*cite journal | author=Carrier F, Georgel PT, Pourquier P, "et al." |title=Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin. |journal=Mol. Cell. Biol. |volume=19 |issue= 3 |pages= 1673–85 |year= 1999 |pmid= 10022855 |doi=
*cite journal | author=Sassone-Corsi P, Mizzen CA, Cheung P, "et al." |title=Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3. |journal=Science |volume=285 |issue= 5429 |pages= 886–91 |year= 1999 |pmid= 10436156 |doi=
*cite journal | author=Thomson S, Clayton AL, Hazzalin CA, "et al." |title=The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase. |journal=EMBO J. |volume=18 |issue= 17 |pages= 4779–93 |year= 1999 |pmid= 10469656 |doi= 10.1093/emboj/18.17.4779
*cite journal | author=Hsieh YJ, Kundu TK, Wang Z, "et al." |title=The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity. |journal=Mol. Cell. Biol. |volume=19 |issue= 11 |pages= 7697–704 |year= 1999 |pmid= 10523658 |doi=
*cite journal | author=Cheung P, Tanner KG, Cheung WL, "et al." |title=Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. |journal=Mol. Cell |volume=5 |issue= 6 |pages= 905–15 |year= 2000 |pmid= 10911985 |doi=
*cite journal | author=Buggy JJ, Sideris ML, Mak P, "et al." |title=Cloning and characterization of a novel human histone deacetylase, HDAC8. |journal=Biochem. J. |volume=350 Pt 1 |issue= |pages= 199–205 |year= 2001 |pmid= 10926844 |doi=
*cite journal | author=Deng L, de la Fuente C, Fu P, "et al." |title=Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. |journal=Virology |volume=277 |issue= 2 |pages= 278–95 |year= 2001 |pmid= 11080476 |doi= 10.1006/viro.2000.0593
*cite journal | author=Seo SB, McNamara P, Heo S, "et al." |title=Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. |journal=Cell |volume=104 |issue= 1 |pages= 119–30 |year= 2001 |pmid= 11163245 |doi=

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