YWHAH

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, also known as YWHAH, is a human gene.

PBB_Summary
section_title =
summary_text = This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. [cite web | title = Entrez Gene: YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7533| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kino T, Pavlakis GN |title=Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1. |journal=DNA Cell Biol. |volume=23 |issue= 4 |pages= 193–205 |year= 2004 |pmid= 15142377 |doi= 10.1089/104454904773819789
*cite journal | author=Kino T, Chrousos GP |title=Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome? |journal=Ann. N. Y. Acad. Sci. |volume=1024 |issue= |pages= 153–67 |year= 2004 |pmid= 15265780 |doi= 10.1196/annals.1321.013
*cite journal | author=Ichimura-Ohshima Y, Morii K, Ichimura T, "et al." |title=cDNA cloning and chromosome assignment of the gene for human brain 14-3-3 protein eta chain. |journal=J. Neurosci. Res. |volume=31 |issue= 4 |pages= 600–5 |year= 1992 |pmid= 1578511 |doi= 10.1002/jnr.490310403
*cite journal | author=Ichimura T, Isobe T, Okuyama T, "et al." |title=Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 19 |pages= 7084–8 |year= 1988 |pmid= 2902623 |doi=
*cite journal | author=Ichimura T, Uchiyama J, Kunihiro O, "et al." |title=Identification of the site of interaction of the 14-3-3 protein with phosphorylated tryptophan hydroxylase. |journal=J. Biol. Chem. |volume=270 |issue= 48 |pages= 28515–8 |year= 1996 |pmid= 7499362 |doi=
*cite journal | author=Jones DH, Ley S, Aitken A |title=Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins. |journal=FEBS Lett. |volume=368 |issue= 1 |pages= 55–8 |year= 1995 |pmid= 7615088 |doi=
*cite journal | author=Wu C, Friedlander P, Lamoureux C, "et al." |title=cDNA clones contain autonomous replication activity. |journal=Biochim. Biophys. Acta |volume=1174 |issue= 3 |pages= 241–57 |year= 1993 |pmid= 7690594 |doi=
*cite journal | author=Swanson KD, Dhar MS, Joshi JG |title=The human and bovine 14-3-3 eta protein mRNAs are highly conserved in both their translated and untranslated regions. |journal=Biochim. Biophys. Acta |volume=1216 |issue= 1 |pages= 145–8 |year= 1993 |pmid= 8218406 |doi=
*cite journal | author=Leffers H, Madsen P, Rasmussen HH, "et al." |title=Molecular cloning and expression of the transformation sensitive epithelial marker stratifin. A member of a protein family that has been involved in the protein kinase C signalling pathway. |journal=J. Mol. Biol. |volume=231 |issue= 4 |pages= 982–98 |year= 1993 |pmid= 8515476 |doi= 10.1006/jmbi.1993.1346
*cite journal | author=Muratake T, Hayashi S, Ichimura Y, "et al." |title=The effect on methamphetamine on the mRNA level for 14.3.3 eta chain in the human cultured cells. |journal=Mol. Neurobiol. |volume=11 |issue= 1-3 |pages= 223–30 |year= 1996 |pmid= 8561965 |doi=
*cite journal | author=Tommerup N, Leffers H |title=Assignment of the human genes encoding 14,3-3 Eta (YWHAH) to 22q12, 14-3-3 zeta (YWHAZ) to 2p25.1-p25.2, and 14-3-3 beta (YWHAB) to 20q13.1 by in situ hybridization. |journal=Genomics |volume=33 |issue= 1 |pages= 149–50 |year= 1996 |pmid= 8617504 |doi= 10.1006/geno.1996.0176
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Papin C, Denouel A, Calothy G, Eychène A |title=Identification of signalling proteins interacting with B-Raf in the yeast two-hybrid system. |journal=Oncogene |volume=12 |issue= 10 |pages= 2213–21 |year= 1996 |pmid= 8668348 |doi=
*cite journal | author=Vincenz C, Dixit VM |title=14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules. |journal=J. Biol. Chem. |volume=271 |issue= 33 |pages= 20029–34 |year= 1996 |pmid= 8702721 |doi=
*cite journal | author=Muratake T, Hayashi S, Ichikawa T, "et al." |title=Structural organization and chromosomal assignment of the human 14-3-3 eta chain gene (YWHAH). |journal=Genomics |volume=36 |issue= 1 |pages= 63–9 |year= 1997 |pmid= 8812417 |doi= 10.1006/geno.1996.0426
*cite journal | author=Wakui H, Wright AP, Gustafsson J, Zilliacus J |title=Interaction of the ligand-activated glucocorticoid receptor with the 14-3-3 eta protein. |journal=J. Biol. Chem. |volume=272 |issue= 13 |pages= 8153–6 |year= 1997 |pmid= 9079630 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Peng CY, Graves PR, Thoma RS, "et al." |title=Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. |journal=Science |volume=277 |issue= 5331 |pages= 1501–5 |year= 1997 |pmid= 9278512 |doi=
*cite journal | author=De Valck D, Heyninck K, Van Criekinge W, "et al." |title=A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins. |journal=Biochem. Biophys. Res. Commun. |volume=238 |issue= 2 |pages= 590–4 |year= 1997 |pmid= 9299557 |doi= 10.1006/bbrc.1997.7343
*cite journal | author=Hsu SY, Kaipia A, Zhu L, Hsueh AJ |title=Interference of BAD (Bcl-xL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11. |journal=Mol. Endocrinol. |volume=11 |issue= 12 |pages= 1858–67 |year= 1997 |pmid= 9369453 |doi=

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